S
So Hee Lim
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 4
Citations - 209
So Hee Lim is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: PTPRT & Gene. The author has an hindex of 3, co-authored 3 publications receiving 155 citations. Previous affiliations of So Hee Lim include Chungnam National University.
Papers
More filters
Journal ArticleDOI
De Novo Mutations in the Motor Domain of KIF1A Cause Cognitive Impairment, Spastic Paraparesis, Axonal Neuropathy, and Cerebellar Atrophy
Jae-Ran Lee,Myriam Srour,Doyoun Kim,Fadi F. Hamdan,So Hee Lim,Catherine Brunel-Guitton,Jean Claude Décarie,Elsa Rossignol,Grant A. Mitchell,Allison Schreiber,Rocio Moran,Keith Van Haren,Randal Richardson,Joost Nicolai,Karin M E J Oberndorff,Justin D. Wagner,Kym M. Boycott,Elisa Rahikkala,Nella Junna,Henna Tyynismaa,Inge Cuppen,Nienke E. Verbeek,Connie T.R.M. Stumpel,Michèl A.A.P. Willemsen,Sonja A. de Munnik,Guy A. Rouleau,Eunjoon Kim,Erik-Jan Kamsteeg,Tjitske Kleefstra,Jacques L. Michaud +29 more
TL;DR: It is indicated that de novo missense mutations in the MD of KIF1A cause a phenotype that overlaps with, while being more severe, than that associated with recessive mutation in the same gene.
Journal ArticleDOI
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.
So Hee Lim,So Hee Lim,Seok-Kyu Kwon,Myung Kyu Lee,Jeonghee Moon,Dae Gwin Jeong,Eunha Park,Seung Jun Kim,Byung Chul Park,Sang Chul Lee,Seong Eon Ryu,Dae Yeul Yu,Bong Hyun Chung,Eunjoon Kim,Pyung Keun Myung,Jae-Ran Lee +15 more
TL;DR: It is suggested that brain‐specific PTPRT regulates synapse formation through interaction with cell adhesion molecules, and this function and the phosphatase activity are attenuated through tyrosine phosphorylation by the synaptic tyrosinesine kinase Fyn.
Journal ArticleDOI
Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis
So Hee Lim,So Hee Lim,Sangyep Shin,Myoung Hwan Kim,Eung Chang Kim,Da Yong Lee,Jeonghee Moon,Hye Yeon Park,Ryu Young Kyoung,Young Mi Kang,Yu Jeong Kang,Tae Hwan Kim,Na Yoon Lee,Nam Soon Kim,Dae Yeul Yu,Insop Shim,Yoichi Gondo,Masanobu Satake,Eunhee Kim,Kyoung Shim Kim,Sun Seek Min,Jae-Ran Lee +21 more
TL;DR: The findings show that the physiological roles of PTPRT in hippocampal neurogenesis and synaptic function are involved in the pathogenesis of depressive disorder.
Journal ArticleDOI
Size-Dependent Effects of Polystyrene Nanoparticles (PS-NPs) on Behaviors and Endogenous Neurochemicals in Zebrafish Larvae
Kyu Seok Hwang,Yu Jin Son,Seong Soon Kim,Dae-Seop Shin,So Hee Lim,Jung Yoon Yang,Ha Neul Jeong,Byung Hoi Lee,Myung Ae Bae +8 more
TL;DR: This study exposed zebrafish larvae to two types of fluorescent polystyrene nanoparticles to identify their size-dependent effects and concluded that small nanoparticles disturb the nervous system, especially dopaminergic metabolites.