S
Somak Roy
Researcher at University of Pittsburgh
Publications - 68
Citations - 4006
Somak Roy is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Medicine & Health informatics. The author has an hindex of 18, co-authored 56 publications receiving 2887 citations. Previous affiliations of Somak Roy include Maulana Azad Medical College.
Papers
More filters
Journal ArticleDOI
Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists
Marilyn M. Li,Michael B. Datto,Eric J. Duncavage,Shashikant Kulkarni,Neal I. Lindeman,Somak Roy,Apostolia Maria Tsimberidou,Cindy L. Vnencak-Jones,Daynna J. Wolff,Anas Younes,Marina N. Nikiforova +10 more
TL;DR: A four-tiered system to categorize somatic sequence variations based on their clinical significances is proposed, with variants with strong clinical significance and variants with potential clinical significance in tier I; tier III, variants of unknown clinical significance; and tier IV, variants deemed benign or likely benign.
Journal ArticleDOI
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.
W. Marston Linehan,Paul T. Spellman,Christopher J. Ricketts,Chad J. Creighton,Suzanne S. Fei,Caleb F. Davis,David A. Wheeler,Bradley A. Murray,Laura S. Schmidt,Cathy D. Vocke,Myron Peto,Abu Amar M. Al Mamun,Eve Shinbrot,Anurag Sethi,Samira A. Brooks,W. Kimryn Rathmell,Angela N. Brooks,Katherine A. Hoadley,A. Gordon Robertson,Denise Brooks,Reanne Bowlby,Sara Sadeghi,Hui Shen,Daniel J. Weisenberger,Moiz S. Bootwalla,Stephen B. Baylin,Peter W. Laird,Andrew D. Cherniack,Gordon Saksena,Scott M. Haake,Jun Li,Han Liang,Yiling Lu,Gordon B. Mills,Rehan Akbani,Mark D.M. Leiserson,Benjamin J. Raphael,Pavana Anur,Donald P. Bottaro,Laurence Albiges,Nandita Barnabas,Toni K. Choueiri,Bogdan Czerniak,Andrew K. Godwin,A. Ari Hakimi,Thai H. Ho,James J. Hsieh,Michael M. Ittmann,William Y. Kim,Bhavani Krishnan,Maria Merino,Kenna R. Mills Shaw,Victor E. Reuter,Ed Reznik,Carl Simon Shelley,Brian Shuch,Sabina Signoretti,Ramaprasad Srinivasan,Pheroze Tamboli,George Thomas,Satish K. Tickoo,Kenneth Burnett,Daniel Crain,Johanna Gardner,Kevin Lau,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,W. Troy Shelton,Mark E. Sherman,Eric M. Thompson,Peggy Yena,Melissa T. Avedon,Jay Bowen,Julie M. Gastier-Foster,Mark Gerken,Kristen M. Leraas,Tara M. Lichtenberg,Nilsa C. Ramirez,Tracie Santos,Lisa Wise,Erik Zmuda,John A. Demchok,Ina Felau,Carolyn M. Hutter,Margi Sheth,Heidi J. Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean C. Zenklusen,Jiashan Zhang,Brenda Ayala,Julien Baboud,Sudha Chudamani,Jia Liu,Laxmi Lolla,Rashi Naresh,Todd Pihl,Qiang Sun,Yunhu Wan,Ye Wu,Adrian Ally,Miruna Balasundaram,Saianand Balu,Rameen Beroukhim,Tom Bodenheimer,Christian J. Buhay,Yaron S.N. Butterfield,Rebecca Carlsen,Scott L. Carter,Hsu Chao,Eric Chuah,Amanda Clarke,Kyle R. Covington,Mahmoud Dahdouli,Ninad Dewal,Noreen Dhalla,Harsha Doddapaneni,Jennifer Drummond,Stacey Gabriel,Richard A. Gibbs,Ranabir Guin,Walker Hale,Alicia Hawes,D. Neil Hayes,Robert A. Holt,Alan P. Hoyle,Stuart R. Jefferys,Steven J.M. Jones,Corbin D. Jones,Divya Kalra,Christie Kovar,Lora Lewis,Jie Li,Yussanne Ma,Marco A. Marra,Michael Mayo,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Richard A. Moore,Donna Morton,Lisle E. Mose,Andrew J. Mungall,Donna M. Muzny,Joel S. Parker,Charles M. Perou,Jeffrey Roach,Jacqueline E. Schein,Steven E. Schumacher,Yan Shi,Janae V. Simons,Payal Sipahimalani,Tara Skelly,Matthew G. Soloway,Carrie Sougnez,Angela Tam,Donghui Tan,Nina Thiessen,Umadevi Veluvolu,Min Wang,Matthew D. Wilkerson,Tina Wong,Junyuan Wu,Liu Xi,Jane Zhou,Jason Bedford,Fengju Chen,Yao Fu,Mark Gerstein,David Haussler,Katayoon Kasaian,Phillip H. Lai,Shiyun Ling,Amie Radenbaugh,David Van Den Berg,John N. Weinstein,Jingchun Zhu,Monique Albert,Iakovina Alexopoulou,Jeremiah J. Andersen,J. Todd Auman,John Bartlett,Sheldon I. Bastacky,Julie Bergsten,Michael L. Blute,Lori Boice,Roni J. Bollag,Jeff Boyd,Erik P. Castle,Ying-Bei Chen,John C. Cheville,Erin Curley,Benjamin Davies,April DeVolk,Rajiv Dhir,Laura Dike,John Eckman,Jay Engel,Jodi Harr,Ronald L. Hrebinko,Mei Huang,Lori Huelsenbeck-Dill,Mary Iacocca,Bruce L. Jacobs,Michael Lobis,Jodi K. Maranchie,Scott McMeekin,Jerome Myers,Joel Nelson,Jeremy Parfitt,Anil V. Parwani,Nicholas J. Petrelli,Brenda Rabeno,Somak Roy,Andrew Salner,Joel Slaton,Melissa L. Stanton,R. Houston Thompson,Leigh B. Thorne,Kelinda Tucker,Paul M. Weinberger,Cynthia Winemiller,Leigh Anne Zach,Rosemary E. Zuna +227 more
TL;DR: Type 1 and type 2 papillary renal-cell carcinomas were shown to be different types of renal cancer characterized by specific genetic alterations, with type 2 further classified into three individual subgroups on the basis of molecular differences associated with patient survival.
Journal ArticleDOI
Targeted Next-Generation Sequencing Panel (ThyroSeq) for Detection of Mutations in Thyroid Cancer
TL;DR: The ThyroSeq NGS panel allows simultaneous testing for multiple mutations with high accuracy and sensitivity, requires a small amount of DNA and can be performed in a variety of thyroid tissue and fine-needle aspiration samples, and provides quantitative assessment of mutant alleles.
Journal ArticleDOI
Standards and Guidelines for Validating Next-Generation Sequencing Bioinformatics Pipelines: A Joint Recommendation of the Association for Molecular Pathology and the College of American Pathologists.
Somak Roy,Christopher Coldren,Arivarasan Karunamurthy,Nefize S. Kip,Eric W. Klee,Stephen E Lincoln,Annette Leon,Mrudula Pullambhatla,Robyn L. Temple-Smolkin,Karl V. Voelkerding,Chen Wang,Alexis B. Carter +11 more
TL;DR: The Association of Molecular Pathology, with organizational representation from the College of American Pathologists and the American Medical Informatics Association, has developed a set of 17 best practice consensus recommendations for the validation of clinical NGS bioinformatics pipelines.
Journal ArticleDOI
Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers
Aatur D. Singhi,Ben George,Joel R. Greenbowe,Jon Chung,James Suh,Anirban Maitra,Samuel J. Klempner,Andrew Eugene Hendifar,Javle Milind,Talia Golan,Randall E. Brand,Amer H. Zureikat,Somak Roy,Alexa B. Schrock,Vincent A. Miller,Jeffrey S. Ross,Siraj M. Ali,Nathan Bahary +17 more
TL;DR: In targeted genomic profile analyses of 3594 PDACs, 17% were found to contain genomic alterations that might make the tumor cells susceptible to currently used anticancer agents and these alterations might be used as biomarkers for early detection.