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Erik P. Castle

Researcher at Mayo Clinic

Publications -  212
Citations -  10397

Erik P. Castle is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Cystectomy & Nephrectomy. The author has an hindex of 42, co-authored 208 publications receiving 8187 citations. Previous affiliations of Erik P. Castle include University of Arkansas for Medical Sciences & Tulane University.

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Journal ArticleDOI

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Katherine A Hoadley, +738 more
- 05 Apr 2018 - 
TL;DR: Molecular similarities among histologically or anatomically related cancer types provide a basis for focused pan-cancer analyses, such as pan-gastrointestinal, Pan-gynecological, pan-kidney, and pan-squamous cancers, and those related by stemness features, which may inform strategies for future therapeutic development.
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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

W. Marston Linehan, +227 more
TL;DR: Type 1 and type 2 papillary renal-cell carcinomas were shown to be different types of renal cancer characterized by specific genetic alterations, with type 2 further classified into three individual subgroups on the basis of molecular differences associated with patient survival.
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Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Alison M. Taylor, +732 more
- 09 Apr 2018 - 
TL;DR: The genomic and phenotypic correlates of cancer aneuploidy are defined and genome engineering is applied to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
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Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial

TL;DR: In patients with bladder cancer, robotic Cystectomy was non-inferior to open cystectomy for 2-year progression-free survival and increased adoption of robotic surgery in clinical practice should lead to future randomised trials to assess the true value of this surgical approach in patients with other cancer types.
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Diagnosis, Evaluation and Follow-Up of Asymptomatic Microhematuria (AMH) in Adults: AUA Guideline

TL;DR: This guideline provides a clinical framework for the diagnosis, evaluation and follow-up of asymptomatic microhematuria and identifies multiphasic computed tomography as the preferred imaging technique and developed guideline statements for persistent or recurrent AMH as well as follow- up.