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Gordon Saksena

Researcher at Broad Institute

Publications -  53
Citations -  51593

Gordon Saksena is an academic researcher from Broad Institute. The author has contributed to research in topics: Germline mutation & DNA methylation. The author has an hindex of 42, co-authored 53 publications receiving 41394 citations. Previous affiliations of Gordon Saksena include University of Colorado Denver & Cornell University.

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Integrated genomic analyses of ovarian carcinoma

Daphne W. Bell, +261 more
TL;DR: The Cancer Genome Atlas project has analyzed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumours as mentioned in this paper.
Journal Article

The Cancer Genome Atlas Pan-Cancer analysis project

Kyle Chang, +337 more
- 01 Sep 2013 - 
TL;DR: The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels as mentioned in this paper.
Journal ArticleDOI

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass, +257 more
- 11 Sep 2014 - 
TL;DR: A comprehensive molecular evaluation of 295 primary gastric adenocarcinomas as part of The Cancer Genome Atlas (TCGA) project is described and a molecular classification dividing gastric cancer into four subtypes is proposed.
Journal ArticleDOI

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence, +96 more
- 11 Jul 2013 - 
TL;DR: A fundamental problem with cancer genome studies is described: as the sample size increases, the list of putatively significant genes produced by current analytical methods burgeons into the hundreds and the list includes many implausible genes, suggesting extensive false-positive findings that overshadow true driver events.
Journal ArticleDOI

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

Eric A. Collisson, +318 more
- 01 Jan 2014 - 
TL;DR: In this paper, the authors report molecular profiling of 230 resected lung adnocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, methylation and proteomic analyses.