S
Sonal Nagarkar-Jaiswal
Researcher at Baylor College of Medicine
Publications - 23
Citations - 1283
Sonal Nagarkar-Jaiswal is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Gene & Motor neuron. The author has an hindex of 13, co-authored 22 publications receiving 1011 citations. Previous affiliations of Sonal Nagarkar-Jaiswal include University of Bayreuth & Center for Cell and Gene Therapy.
Papers
More filters
Journal ArticleDOI
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila.
Sonal Nagarkar-Jaiswal,Pei-Tseng Lee,Megan Campbell,Kuchuan Chen,Stephanie Anguiano-Zarate,Manuel Cantu Gutierrez,Theodore Busby,Wen-Wen Lin,Yuchun He,Karen L. Schulze,Benjamin W. Booth,Martha Evans-Holm,Koen J. T. Venken,Robert W. Levis,Allan C. Spradling,Roger A. Hoskins,Hugo J. Bellen +16 more
TL;DR: A collection of MiMIC (Minos Mediated Integration Cassette) insertions allowed us to create a library of 400 GFP-tagged genes and it is shown that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues.
Journal ArticleDOI
Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila
Liming Tan,Kelvin Xi Zhang,Matthew Y. Pecot,Sonal Nagarkar-Jaiswal,Pei-Tseng Lee,Shin-ya Takemura,Jason M. McEwen,Aljoscha Nern,Shuwa Xu,Wael Tadros,Zhenqing Chen,Kai Zinn,Hugo J. Bellen,Marta Morey,S. Lawrence Zipursky +14 more
TL;DR: This work shows that neurons with different synaptic specificities express unique combinations of mRNAs encoding hundreds of cell surface and secreted proteins, and proposes that pairs of Dpr/DIP paralogs contribute to layer-specific patterns of synaptic connectivity.
Journal ArticleDOI
Single-cell analysis of transcription kinetics across the cell cycle
Samuel O Skinner,Samuel O Skinner,Samuel O Skinner,Heng Xu,Heng Xu,Heng Xu,Sonal Nagarkar-Jaiswal,Pablo R. Freire,Thomas P. Zwaka,Thomas P. Zwaka,Ido Golding +10 more
TL;DR: In this article, the authors quantified nascent and mature mRNA in individual cells, and incorporated cell-cycle effects in the analysis of mRNA statistics, and demonstrated their approach on Oct4 and Nanog in mouse embryonic stem cells.
Journal ArticleDOI
Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins
Robert A. Carrillo,Engin Özkan,Engin Özkan,Kaushiki P. Menon,Sonal Nagarkar-Jaiswal,Pei-Tseng Lee,Mili Jeon,Mili Jeon,Michael E. Birnbaum,Hugo J. Bellen,K. Christopher Garcia,Kai Zinn +11 more
TL;DR: A network of interacting Drosophila cell surface proteins in which a 21-member IgSF subfamily, the Dprs, binds to a nine-member subfamily), the DIPs, suggests that Dpr-DIP interactions are important determinants of synaptic connectivity.
Journal ArticleDOI
A genetic toolkit for tagging intronic MiMIC containing genes
Sonal Nagarkar-Jaiswal,Steven Z DeLuca,Pei-Tseng Lee,Wen-Wen Lin,Hongling Pan,Zhongyuan Zuo,Jiangxing Lv,Allan C. Spradling,Hugo J. Bellen +8 more
TL;DR: A simple and reliable genetic strategy to tag genes/proteins that contain MiMIC insertions using an integrated exon encoding GFP flanked by FRT sequences is described and document the efficiency and tag 60 mostly uncharacterized genes.