S
Sridevi Devaraj
Researcher at Baylor College of Medicine
Publications - 390
Citations - 23771
Sridevi Devaraj is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Metabolic syndrome & Proinflammatory cytokine. The author has an hindex of 85, co-authored 365 publications receiving 21831 citations. Previous affiliations of Sridevi Devaraj include University of Madras & Boston Children's Hospital.
Papers
More filters
Journal ArticleDOI
Regulation of Inflammatory Phenotype in Macrophages by a Diabetes-Induced Long Noncoding RNA
Marpadga A. Reddy,Zhuo Chen,Jung Tak Park,Mei Wang,Linda Lanting,Qiang Zhang,Kirti Bhatt,Amy Leung,Xiwei Wu,Sumanth Putta,Pål Sætrom,Sridevi Devaraj,Rama Natarajan +12 more
TL;DR: The diabetic macrophage transcriptome is defined and novel functional roles for lncRNAs in macrophages that could lead to lncRNA-based therapies for inflammatory diabetes complications are defined.
Journal ArticleDOI
α-Tocopherol Decreases Interleukin-1β Release From Activated Human Monocytes by Inhibition of 5-Lipoxygenase
Sridevi Devaraj,Ishwarlal Jialal +1 more
TL;DR: In activated human monocytes, AT exerts a novel biological effect of inhibiting the release of the proinflammatory cytokine, IL-1β, via inhibition of the 5-lipoxygenase pathway.
Journal ArticleDOI
Oxidative stress, inflammation, and diabetic vasculopathies: the role of alpha tocopherol therapy.
TL;DR: Alpha tocopherol therapy, especially at high doses, clearly shows a benefit with regards to LDL oxidation, isoprostanes and a decrease in inflammatory markers such as C-reactive protein, pro-inflammatory cytokines and PAI-1 levels, and it appears that, in diabetes, alpha tocop herol therapy could emerge as an additional therapeutic modality.
Journal ArticleDOI
C-Reactive Protein Decreases Tissue Plasminogen Activator Activity in Human Aortic Endothelial Cells Evidence that C-Reactive Protein Is a Procoagulant
TL;DR: This study provides additional novel data that CRP is a procoagulant and has implications for atherothrombosis, and in volunteers that have high CRP levels, euglobulin clot lysis time was significantly increased compared with those that have low CRP Levels, providing further evidence that highCRP levels are associated with a pro coagulants state.
Journal ArticleDOI
α-Tocopherol decreases CD36 expression in human monocyte-derived macrophages
TL;DR: AT decreases both CD36 and SR-A expression and cholesteryl ester accumulation in human macrophages, providing additional scientific support for the antiathero- genic properties of AT.