S
Stanley Goldman
Researcher at Naval Medical Research Center
Publications - 6
Citations - 236
Stanley Goldman is an academic researcher from Naval Medical Research Center. The author has contributed to research in topics: Bacillus anthracis & Antigen. The author has an hindex of 5, co-authored 6 publications receiving 222 citations.
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Journal ArticleDOI
Human Monoclonal Antibodies against Anthrax Lethal Factor and Protective Antigen Act Independently To Protect against Bacillus anthracis Infection and Enhance Endogenous Immunity to Anthrax
Mark T. Albrecht,Han Li,E. Diane Williamson,Chris S. LeButt,Helen C. Flick-Smith,Conrad P. Quinn,Hans Westra,Darrell R. Galloway,Alfred J. Mateczun,Stanley Goldman,Herman Groen,Les Baillie +11 more
TL;DR: Based on results, IQNPA and IQNLF act independently during prophylactic anthrax treatment and do not interfere with the establishment of endogenous immunity.
Journal ArticleDOI
PapR peptide maturation: role of the NprB protease in Bacillus cereus 569 PlcR/PapR global gene regulation
Andrei P. Pomerantsev,Olga M. Pomerantseva,Andrew Camp,Radhika Mukkamala,Stanley Goldman,Stephen H. Leppla +5 more
TL;DR: It is shown that the neutral protease B (NprB) secreted by B. cereus 569 is required for extracellular PapR maturation, and interactions of the C-terminal regions of both PlcR and PapR are important in transcriptional activation of the B. Cereus 5 69 Plc R regulon.
Journal ArticleDOI
The Early Humoral Immune Response to Bacillus anthracis Toxins in Patients Infected with Cutaneous Anthrax
Karen Elaine Brenneman,Karen Elaine Brenneman,Mehmet Doganay,Arya Akmal,Stanley Goldman,Darrell R. Galloway,Darrell R. Galloway,Alfred J. Mateczun,Alan S. Cross,Leslie W. J. Baillie +9 more
TL;DR: The ability of human LF-specific antibodies to neutralize toxin activity supports the possible inclusion of LF in future anthrax vaccines, suggesting the possibility that they may contribute to protection.
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A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge
Vadim Mett,Jessica A. Chichester,Michelle Stewart,Konstantin Musiychuk,Hong Bi,Carolyn J. Reifsnyder,Anna Hull,Mark T. Albrecht,Stanley Goldman,Les Baillie,Vidadi Yusibov +10 more
TL;DR: The potential of a plant-produced non-glycosylated antibody as a useful tool for the treatment of inhalation anthrax is demonstrated and is demonstrated to be superior to pp-mAbPA.
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An Adenovirus-Vectored Nasal Vaccine Confers Rapid and Sustained Protection against Anthrax in a Single-Dose Regimen
Jianfeng Zhang,Edward Jex,Tsungwei Feng,Gloria S. Sivko,Leslie W. Baillie,Stanley Goldman,Kent R. Van Kampen,De-chu C. Tang +7 more
TL;DR: It is reported here that intranasal instillation of a nonreplicating adenovirus vector encoding B. anthracis protective antigen could confer rapid and sustained protection against inhalation anthrax in mice in a single-dose regimen in the presence of preexisting adenvirus immunity.