S
Stefan Lampel
Researcher at University of Oxford
Publications - 4
Citations - 1114
Stefan Lampel is an academic researcher from University of Oxford. The author has contributed to research in topics: Analyte & Dynein. The author has an hindex of 3, co-authored 4 publications receiving 1075 citations.
Papers
More filters
Journal ArticleDOI
Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport
Majid Hafezparast,Rainer Klocke,Christiana Ruhrberg,Andreas Marquardt,Azlina Ahmad-Annuar,Samantha Bowen,Giovanna Lalli,Abi S. Witherden,Holger Hummerich,Sharon E. Nicholson,P. Jeffrey Morgan,Ravi Oozageer,John V. Priestley,Sharon Averill,V.R. King,Simon T. Ball,Jo Peters,Takashi Toda,Ayumu Yamamoto,Yasushi Hiraoka,Martin Augustin,Dirk Korthaus,Sigrid Wattler,Philipp Wabnitz,Carmen Dickneite,Stefan Lampel,Florian Boehme,Gisela Peraus,Andreas Popp,Martina Rudelius,Juergen Schlegel,Helmut Fuchs,Martin Hrabé de Angelis,Giampietro Schiavo,David T. Shima,Andreas Russ,Gabriele Stumm,Joanne E. Martin,Elizabeth M. C. Fisher +38 more
TL;DR: It is shown that missense point mutations in the cytoplasmic dynein heavy chain result in progressive motor neuron degeneration in heterozygous mice, and in homozygotes this is accompanied by the formation of Lewy-like inclusion bodies, thus resembling key features of human pathology.
Journal ArticleDOI
The druggable genome: an update.
Andreas Russ,Stefan Lampel +1 more
TL;DR: Annotating the druggable genome estimates the potential maximum size of the playing field for current small-molecule drug design but it does not consider biologicals or future breakthroughs in medicinal chemistry or biology.
Patent
Parallel miniaturized quantitative immunoassays
Dorothee Runge,Stefan Lampel,Carmen Dickneite,Volker Schlueter,Thomas O. Joos,Markus F. Templin +5 more
TL;DR: Protein micro-arrays as mentioned in this paper have been used for immunoassay analyses in which antibodies or antigens form the micro-array, and have shown improved performance for automated high-throughput and parallel analyses of multiple parameters.
Patent
Method for determining analyte molecules in a sample
TL;DR: A method for determining the concentration/amount of analyte molecules in the sample comprises the step of: (a) adding to the sample a known concentration/ amount of competitor or analogue molecules of the analyte, said competitor/analogue molecules being distinct from said analyte molecule as mentioned in this paper.