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Andrea M. Füchsl
Researcher at University of Ulm
Publications - 19
Citations - 669
Andrea M. Füchsl is an academic researcher from University of Ulm. The author has contributed to research in topics: Corticosterone & Adrenocorticotropic hormone. The author has an hindex of 13, co-authored 19 publications receiving 557 citations. Previous affiliations of Andrea M. Füchsl include University Hospital Regensburg & University of Regensburg.
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Journal ArticleDOI
Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice
Stefan O. Reber,Philip H. Siebler,Nina C. Donner,James T. Morton,David G. Smith,Jared M. Kopelman,Kenneth R. Lowe,Kristen J. Wheeler,James H. Fox,James E. Hassell,Benjamin N. Greenwood,Charline Jansch,Anja Lechner,Dominic Schmidt,Nicole Uschold-Schmidt,Andrea M. Füchsl,Dominik Langgartner,Frederick R. Walker,Matthew W. Hale,Gerardo Lopez Perez,Will Van Treuren,Antonio Gonzalez,Andrea L. Halweg-Edwards,Monika Fleshner,Charles L. Raison,Graham A. W. Rook,Shyamal D. Peddada,Rob Knight,Christopher A. Lowry +28 more
TL;DR: It is shown that stress disrupts the homeostatic relationship between the microbiota and the host, resulting in exaggerated inflammation, which provides a framework for developing microbiome- and immunoregulation-based strategies for prevention of stress-related pathologies.
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Chronic psychosocial stress results in sensitization of the HPA axis to acute heterotypic stressors despite a reduction of adrenal in vitro ACTH responsiveness
TL;DR: It is shown that chronic psychosocial stressor exposure impairs in vitro ACTH responsiveness of both the left and right adrenal glands, whereas it increases adrenal responsiveness to an acute heterotypic stressor in vivo.
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Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling.
Dominik Langgartner,Andrea M. Füchsl,Nicole Uschold-Schmidt,David A. Slattery,Stefan O. Reber +4 more
TL;DR: The main aim of the current review article is to provide a detailed summary of the behavioral, physiological, neuronal, and immunological consequences of the CSC paradigm, and wherever possible relate the findings to other stress models and to the human situation.
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Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis.
Dominik Langgartner,Daniel Peterlik,Sandra Foertsch,Andrea M. Füchsl,Petra Brokmann,Peter J. Flor,Zeli Shen,James G. Fox,Nicole Uschold-Schmidt,Christopher A. Lowry,Stefan O. Reber +10 more
TL;DR: The data support the hypothesis that the presence or absence of exposure to certain pathobionts contributes to individual variability in susceptibility to stress-/trauma-associated pathologies and to reproducibility of stress-related outcomes between laboratories.
Journal ArticleDOI
Selective Breeding for High Anxiety Introduces a Synonymous SNP That Increases Neuropeptide S Receptor Activity
David A. Slattery,Roshan R. Naik,Thomas Grund,Yi-Chun Yen,Simone B. Sartori,Andrea M. Füchsl,Beate C. Finger,Betina Elfving,Uwe Nordemann,Remo Guerrini,Girolamo Calo,Gregers Wegener,Aleksander A. Mathé,Nicolas Singewald,L. Czibere,Rainer Landgraf,Inga D. Neumann +16 more
TL;DR: Results suggest that alterations in the NPS system, conserved across rodents and humans, contribute to innate anxiety and fear, and that HAB rodents are particularly suited to resolve the apparent discrepancy between the preclinical and clinical findings to date.