Stefania Rossi

TL;DR: Gray matter damage and meningeal inflammation have been associated with early disease onset and a more aggressive disease course in multiple sclerosis, but can these changes be identified in the patient early in the disease course?

TL;DR: The results strengthen previous findings on the immunomodulatory ability of resveratrol and highlight its role as potential therapeutic or preventive compound, to counteract the proatherogenic oxysterol signaling within atherosclerotic plaque.

TL;DR: OCB at MS onset are associated with more severe GM pathology and with a more severe physical disability and cognitive impairment after 10 years, and increased levels of cytokines linked to B cell activation, lymphoid-neogenesis, and pro-inflammatory immune response in the CSF of OCB+ patients support the hypothesis of crucial role played by compartmentalized, intrathecal B cell response inThe pathogenesis of CLs and OCB production.

TL;DR: Inflammatory signals such as TNF and MMP-2 activity are key intrinsic players to determine melanoma cells aggressiveness suggesting new venue sin the identification of novel molecular targets with potential therapeutic relevance.

TL;DR: This work aimed to investigate a detailed proteomic CSF profiling which is able to reflect cortical damage in early MS.