S
Steffen Weber-Carstens
Researcher at Charité
Publications - 188
Citations - 6178
Steffen Weber-Carstens is an academic researcher from Charité. The author has contributed to research in topics: ARDS & Medicine. The author has an hindex of 30, co-authored 165 publications receiving 4378 citations. Previous affiliations of Steffen Weber-Carstens include Humboldt University of Berlin & Humboldt State University.
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Journal ArticleDOI
Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study
Christian Karagiannidis,Carina Mostert,Corinna Hentschker,Thomas Voshaar,Jürgen Malzahn,Gerhard Schillinger,Jürgen Klauber,Uwe Janssens,Gernot Marx,Steffen Weber-Carstens,Stefan Kluge,Michael Pfeifer,Linus Grabenhenrich,Tobias Welte,Reinhard Busse +14 more
TL;DR: In the German health-care system, in which hospital capacities have not been overwhelmed by the COVID-19 pandemic, mortality has been high for patients receiving mechanical ventilation, particularly for patients aged 80 years or older and those requiring dialysis, and has been considerably lower for patients younger than 60 years.
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Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.
Christian Meisel,Joerg C. Schefold,Rene Pschowski,Tycho Baumann,Katrin Hetzger,Jan Gregor,Steffen Weber-Carstens,Dietrich Hasper,Didier Keh,H. Zuckermann,Petra Reinke,Hans-Dieter Volk +11 more
TL;DR: Biomarker-guided GM-CSF therapy in sepsis is safe and effective for restoring monocytic immunocompetence and may shorten the time of mechanical ventilation and hospital/intensive care unit stay.
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Lower tidal volume strategy (≈3 ml/kg) combined with extracorporeal CO2 removal versus 'conventional' protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study.
Thomas Bein,Steffen Weber-Carstens,Anton Goldmann,Thomas Müller,Thomas Staudinger,Jörg Brederlau,Ralf Michael Muellenbach,Rolf Dembinski,Bernhard M. Graf,Marlene Wewalka,Alois Philipp,Klaus-Dieter Wernecke,Matthias Lubnow,Arthur S. Slutsky +13 more
TL;DR: The use of very low VT ventilation combined with extracorporeal CO2 removal has the potential to further reduce VILI compared with a ‘normal’ lung protective management.
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Intensive care unit—acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock
TL;DR: An insight is provided on the available literature on sepsis-mediated muscle wasting, ICUAW and their potential pathomechanisms, which may lead to increased morbidity and mortality within the intensive care unit (ICU).
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Propagation of cortical spreading depolarization in the human cortex after malignant stroke
Johannes Woitzik,Nils Hecht,Alexandra Pinczolits,Nora Sandow,Sebastian Major,Maren K.L. Winkler,Steffen Weber-Carstens,Christian Dohmen,Rudolf Graf,Anthony J. Strong,Jens P. Dreier,Peter Vajkoczy +11 more
TL;DR: The data suggest that, in patients with focal ischemia, cortical spreading depolarizations are associated with both unfavorable and protective hemodynamic responses, and spatiotemporal propagation in the human cerebral cortex intraoperatively is visualize.