Steffi Grote

TL;DR: The genome of a female Neandertal from ~50,000 years ago from Vindija Cave, Croatia, is sequenced to ~30-fold genomic coverage, allowing 10 to 20% more Ne andertal DNA to be identified in present-day humans, including variants involved in low-density lipoprotein cholesterol concentrations, schizophrenia, and other diseases.

TL;DR: This work developed an approach to identify DNA inherited from multiple archaic hominin ancestors and applied it to whole-genome sequences from 1523 geographically diverse individuals, including 35 previously unknown Island Melanesian genomes, and recovered Neandertal and Denisovan DNA.

TL;DR: The genome of ‘Denisova 11’, a bone fragment from Denisova Cave (Russia) is presented and it is shown that it comes from an individual who had a Neanderthal mother and a Denisovan father.

TL;DR: It is found that the bulk of Neanderthal gene flow into early modern humans originated from one or more source populations that diverged from the Neanderthals that were studied here at least 70,000 years ago, but after they split from a previously sequenced Neanderthal from Siberia around 150,000 year ago.

TL;DR: The genome of a Neandertal from Chagyrskaya Cave in the Altai Mountains, Russia, is sequenced to 27-fold genomic coverage and it is found that genes highly expressed in the Striatum in the basal ganglia of the brain carry more amino-acid-changing substitutions than genes expressed elsewhere in the brain, suggesting that the striatum may have evolved unique functions in NeandERTals.