Stephen M Griffey

TL;DR: It is demonstrated that disease-associated autoreactive T cells from patients with type-1 diabetes mellitus or rheumatoid arthritis are mainly CD4+CCR7−CD45RA− effector memory T cells (TEM cells) with elevated Kv1.3 potassium channel expression, which ameliorate pristane-induced arthritis in rats and reduce the incidence of experimental autoimmune diabetes in diabetes-prone rats.

TL;DR: In this article, the authors report the pathologic consequences of Zmpste24 deficiency in mice, including multiple spontaneous bone fractures and muscle weakness in the lower and upper extremities, resembling mice lacking the farnesylated CAAX protein prelamin A.

TL;DR: It is demonstrated that a KD extends longevity and healthspan in mice and regulated mTORC1 signaling in a tissue-dependent manner.

TL;DR: Intraoperative RF ablation results in invasive breast cancer cell death and this technique merits further investigation as a percutaneous minimally invasive modality for the local treatment of breast cancer.

TL;DR: The results demonstrate the feasibility of percutaneous ultrasound-guided RF electrocautery ablation of canine prostate tissue and demonstrate that the treatment area included a central area of char with a surrounding area of coagulation.