S
Stuart McDonald
Researcher at University of Queensland
Publications - 314
Citations - 10116
Stuart McDonald is an academic researcher from University of Queensland. The author has contributed to research in topics: Eutectic system & Intermetallic. The author has an hindex of 52, co-authored 289 publications receiving 8679 citations. Previous affiliations of Stuart McDonald include Lincoln's Inn & St Bartholomew's Hospital.
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Journal ArticleDOI
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
Laura C. Greaves,Sean L. Preston,Paul J. Tadrous,Robert W. Taylor,Martin J. Barron,Dahmane Oukrif,Simon J. Leedham,Maesha Deheragoda,Peter Sasieni,Marco Novelli,Janusz Jankowski,Douglass M. Turnbull,Nicholas A. Wright,Stuart McDonald +13 more
TL;DR: It is demonstrated definitively that crypt fission is the mechanism by which mutations spread in the normal human colon, which has important implications for the biology of the normal adult human colon and possibly for the growth and spread of colorectal neoplasms.
Journal ArticleDOI
Eutectic modification and microstructure development in Al–Si Alloys
TL;DR: In this article, the state-of-the-art in understanding the mechanism of eutectic nucleation and growth in Al-Si alloys, inspecting samples, both quenched and uninterrupted, on the macro, micro and nano-scale.
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Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells.
Stuart McDonald,Stuart McDonald,Laura C. Greaves,Lydia Gutierrez–Gonzalez,Manuel Rodriguez–Justo,Maesha Deheragoda,Maesha Deheragoda,Simon J. Leedham,Robert W. Taylor,Chung Yin Lee,Sean L. Preston,Matthew A. Lovell,Toby Hunt,George Elia,Dahmane Oukrif,Rebecca Harrison,Marco Novelli,I Mitchell,David L. Stoker,Douglass M. Turnbull,Janusz Jankowski,Janusz Jankowski,Janusz Jankowski,Nicholas A. Wright,Nicholas A. Wright +24 more
TL;DR: The data show that human gastric body units are clonal, contain multiple multipotential stem cells, and provide definitive evidence for how mutations spread within the human stomach, and show how field cancerization develops.
Journal ArticleDOI
Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies.
Rebecca Harrison,Ian Perry,William Haddadin,Stuart McDonald,Richard T. Bryan,Keith R. Abrams,Richard E. Sampliner,Nicholas J. Talley,Paul Moayyedi,Janusz Jankowski +9 more
TL;DR: The data suggest that at least 8 random biopsies is the minimum to be taken and analyzed with conventional H&E staining to diagnose benign intestinal metaplasia.
Journal ArticleDOI
Eutectic nucleation and growth in hypoeutectic Al-Si alloys at different strontium levels
TL;DR: In this article, the effects of different levels of strontium on nucleation and growth of the eutectic in a commercial hypoeutective Al-Si foundry alloy have been investigated by optical microscopy and electron backscattering diffraction (EBSD) mapping by scanning electron microscopy (SEM).