S
Sui-Yuan Chang
Researcher at National Taiwan University
Publications - 212
Citations - 4583
Sui-Yuan Chang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Medicine & Men who have sex with men. The author has an hindex of 32, co-authored 169 publications receiving 3551 citations. Previous affiliations of Sui-Yuan Chang include Academia Sinica & Harvard University.
Papers
More filters
Journal ArticleDOI
Prolonged virus shedding even after seroconversion in a patient with COVID-19.
Wang Da Liu,Sui-Yuan Chang,Jann-Tay Wang,Ming Jui Tsai,Chien-Ching Hung,Chia-Lin Hsu,Shan-Chwen Chang +6 more
TL;DR: Viral detection from throat gargling sample could be an alternative diagnostic method for mild COVID-19 patients with scarce sputum andSputum remained the most sensitive specimen for viral detection after clinical symptoms resolved.
Journal ArticleDOI
Human TLR3 recognizes dengue virus and modulates viral replication in vitro
TL;DR: It is found that the expression of TLR3 can mediate strong IFN‐α/β release and inhibit DENV viral replication significantly, thus limit the cytopathic effect.
Journal ArticleDOI
Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects
Ya-Wen Cheng,Tai Ling Chao,Chiao Ling Li,Mu Fan Chiu,Han Chieh Kao,Sheng-Han Wang,Yu Hao Pang,Chih Hui Lin,Ya Min Tsai,Wen Hau Lee,Mi-Hua Tao,Tung Ching Ho,Ping-Yi Wu,Li Ting Jang,Pei-Jer Chen,Sui-Yuan Chang,Shiou-Hwei Yeh +16 more
TL;DR: Host proteases that proteolytically activate the SARS-CoV-2 spike protein, critical for its fusion after binding to angiotensin-converting enzyme 2 (ACE2), as antiviral targets are focused on.
Journal ArticleDOI
Human Immunodeficiency Virus Type 1 Subtype C Molecular Phylogeny: Consensus Sequence for an AIDS Vaccine Design?
Vladimir Novitsky,U. R. Smith,Peter B. Gilbert,MF McLane,Pride Chigwedere,Carolyn Williamson,Thumbi Ndung'u,Isaac A. Klein,Sui-Yuan Chang,Trevor Peter,Ibou Thior,Brian T. Foley,S. Gaolekwe,Natasha Rybak,Simani Gaseitsiwe,Fredrik O. Vannberg,Richard Marlink,Tak H. Lee,Max Essex +18 more
TL;DR: It is suggested that the consensus sequence approach could overcome the high genetic diversity of HIV-1C and facilitate an AIDS vaccine design, particularly if the assumption that an HIV- 1C antigen with a more extensive match to the circulating viruses is likely to be more efficacious is proven in efficacy trials.
Journal ArticleDOI
Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E.
Bing Ching Ho,Sung-Liang Yu,Jeremy J.W. Chen,Jeremy J.W. Chen,Sui-Yuan Chang,Bo-Shiun Yan,Qi Sheng Hong,Sher Singh,Chuan-Liang Kao,Hsuan-Yu Chen,Hsuan-Yu Chen,Kang-Yi Su,Kang-Yi Su,Ker-Chau Li,Chiou Ling Cheng,Hao Wei Cheng,Jen Yi Lee,Chun Nan Lee,Pan-Chyr Yang,Pan-Chyr Yang +19 more
TL;DR: The results suggest that upregulation of miR-141 upon enterovirus infection can facilitate viral propagation by expediting the translational switch, and identify a transcription factor, EGR1, which is partly responsible for mi R-141 induction in response to enterov virus infection.