S
Suk Yun Kang
Researcher at Seoul National University
Publications - 34
Citations - 784
Suk Yun Kang is an academic researcher from Seoul National University. The author has contributed to research in topics: Neuropathic pain & Nociception. The author has an hindex of 18, co-authored 30 publications receiving 674 citations.
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Journal ArticleDOI
Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABAA receptors
Seo Yeon Yoon,Dae Hyun Roh,Hyoung Sig Seo,Suk Yun Kang,Ho Jae Han,Alvin J. Beitz,Jang Hern Lee +6 more
TL;DR: This study was designed to examine whether intrathecally injected DHEAS or DHEA affect nociceptive signalling at the spinal cord level.
Journal ArticleDOI
Spinal sigma-1 receptor activation increases the production of d-serine in astrocytes which contributes to the development of mechanical allodynia in a mouse model of neuropathic pain.
Jiyoung Moon,Sheu Ran Choi,Dae Hyun Roh,Seo Yeon Yoon,Soon Gu Kwon,Hoon Seong Choi,Suk Yun Kang,Ho Jae Han,Hyun-Woo Kim,Alvin J. Beitz,Seog Bae Oh,Jang Hern Lee +11 more
TL;DR: These findings demonstrate for the first time that the activation of Sig-1Rs increases the expression of Srr and d-serine in astrocytes and ultimately affects dorsal horn neurons that are involved in the development of MA in neuropathic mice.
Journal ArticleDOI
Low-frequency electroacupuncture suppresses zymosan-induced peripheral inflammation via activation of sympathetic post-ganglionic neurons.
Hyun-Woo Kim,Suk Yun Kang,Seo Yeon Yoon,Dae Hyun Roh,Young Bae Kwon,Ho Jae Han,Hyejung Lee,Alvin J. Beitz,Jang Hern Lee +8 more
TL;DR: Results suggest that EA produces an anti-inflammatory effect in this mouse air pouch model by activating the sympathetic nervous system leading to the release of catecholamines from post-ganglionic nerve terminals, which act on beta-adrenoceptors on immune cells to inhibit their migration.
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Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.
Sheu Ran Choi,Jiyoung Moon,Dae Hyun Roh,Seo Yeon Yoon,Soon Gu Kwon,Hoon Seong Choi,Suk Yun Kang,Ho Jae Han,Alvin J. Beitz,Jang Hern Lee +9 more
TL;DR: In this article, spinal sigma-1 receptor (Sig-1R) activation facilitates nociception via an increase in phosphorylation of the N -methyl-D-aspartate (NMDA) receptor GluN1 subunit.
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Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.
Soon Gu Kwon,Dae Hyun Roh,Seo Yeon Yoon,Jiyoung Moon,Sheu Ran Choi,Hoon Seong Choi,Suk Yun Kang,Ho Jae Han,Alvin J. Beitz,Seog B. Oh,Jang Hern Lee +10 more
TL;DR: In this article, a thrombus-induced ischemic pain (TIIP) animal model was developed, which was characterized by chronic bilateral mechanical allodynia without thermal hyperalgesia (TH).