Suk Yun Kang

TL;DR: DBV stimulation of the ST36 acupoint inhibits the formalin-induced activation of spinal astrocytes and nociceptive behaviors in this inflammatory pain model and this inhibition is associated with theactivation of spinal alpha-2 adrenoceptors.

TL;DR: The results of the current study demonstrate that peripheral administration of an ASICs blocker or P2X antagonist significantly suppress TIIP, and implicate peripheral ASICs and P2x receptors in the maintenance of thrombus-induced ischemic pain.

TL;DR: It is demonstrated that low tissue pH facilitates ATP-mediated MA via the activation of P2X receptors and ASICs, whereas TH induced by ATP under low pH conditions is mediated by the P2Y1 receptor and TRPV1, but not ASIC.

TL;DR: It is demonstrated that spinal activation of Nav1.8 mediates the early induction of MA, but not the maintenance ofMA, and both the induction and maintenance of TH are modulated by the intrathecal injection of Nav 1.8 blockers.

TL;DR: It is shown that spinal D-serine modulates nNOS activity and concomitant NO production leading to increases in PKC-dependent pGluN1 and ultimately contributing to the induction of mechanical allodynia following peripheral nerve injury.