S
Sumanta Goswami
Researcher at Albert Einstein College of Medicine
Publications - 45
Citations - 6375
Sumanta Goswami is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Metastasis & Breast cancer. The author has an hindex of 29, co-authored 42 publications receiving 5871 citations. Previous affiliations of Sumanta Goswami include All India Institute of Medical Sciences & Yeshiva University.
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Journal ArticleDOI
Tumor cells caught in the act of invading: their strategy for enhanced cell motility.
TL;DR: The genes encoding a minimum motility machine are coordinately upregulated in tumor cells collected by an in vivo invasion assay and provide new target opportunities for cancer therapy.
Journal ArticleDOI
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
Weigang Wang,Ghassan Mouneimne,Mazen Sidani,Jeffrey B. Wyckoff,Xiaoming Chen,Anastasia Makris,Sumanta Goswami,Anne R. Bresnick,John S. Condeelis +8 more
TL;DR: The effects of LIMK1 expression on migration, intravasation, and metastasis of cancer cells can be most simply explained by its regulation of the output of the cofilin pathway.
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A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis
Ulrike Philippar,Evanthia T. Roussos,Matthew G. Oser,Hideki Yamaguchi,Hideki Yamaguchi,Hyung-Do Kim,Silvia Giampieri,Yarong Wang,Sumanta Goswami,Sumanta Goswami,Jeffrey B. Wyckoff,Douglas A. Lauffenburger,Erik Sahai,Erik Sahai,John S. Condeelis,Frank B. Gertler +15 more
TL;DR: It is shown that Mena and Mena(INV) promote carcinoma cell motility and invasiveness in vivo and in vitro, and increase lung metastasis and EGF-induced membrane protrusion of tumor cells.
A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis
Ulrike Philippar,Evanthia T. Roussos,Matthew G. Oser,Hideki Yamaguchi,Hideki Yamaguchi,Hyung-Do Kim,Silvia Giampieri,Yarong Wang,Sumanta Goswami,Sumanta Goswami,Jeffrey B. Wyckoff,Douglas A. Lauffenburger,Erik Sahai,Erik Sahai,John S. Condeelis,Frank B. Gertler +15 more
TL;DR: In this paper, Mena and Mena(INV) were shown to promote carcinoma cell motility and invasiveness in vivo and in vitro, and increase lung metastasis.
Journal ArticleDOI
Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor
Antonia Patsialou,Jeffrey B. Wyckoff,Yarong Wang,Sumanta Goswami,E. Richard Stanley,John S. Condeelis +5 more
TL;DR: It is shown here for the first time in vivo that invasion in a human mammary tumor model is dependent on both paracrine signaling with host macrophages as well as autocrine signaling involving the tumor cells themselves.