S
Susan Hudak
Researcher at Schering-Plough
Publications - 21
Citations - 2725
Susan Hudak is an academic researcher from Schering-Plough. The author has contributed to research in topics: Interleukin 4 & Progenitor cell. The author has an hindex of 15, co-authored 21 publications receiving 2671 citations. Previous affiliations of Susan Hudak include Merck & Co..
Papers
More filters
Journal ArticleDOI
Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice.
TL;DR: The results show that interleukin-5 is important in eosinophil production in vivo and that IgE and eosInophils production are regulated by different cytokines produced by the TH2 subset of CD4-expressing T cells.
Journal ArticleDOI
CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells
Janine Morales,Bernhard Homey,Alain Vicari,Susan Hudak,Elizabeth Oldham,Joseph A. Hedrick,Rocio Orozco,Neal G. Copeland,Nancy A. Jenkins,Leslie McEvoy,Albert Zlotnik +10 more
TL;DR: An important role is suggested for CTACK in recruitment of CLA(+) T cells to cutaneous sites and it is suggested that CTACK is predominantly expressed in the skin and selectively attracts a tissue-specific subpopulation of memory lymphocytes.
Journal Article
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice.
TL;DR: It is suggested that IL-12 sustains colitis by supporting the expansion of differentiated Th1 cells that mediate disease independently of their IFN-gamma production.
Journal Article
The CC Chemokine Receptor-7 Ligands 6Ckine and Macrophage Inflammatory Protein-3β Are Potent Chemoattractants for In Vitro- and In Vivo-Derived Dendritic Cells
TL;DR: Using a novel transwell chemotaxis assay system, it is demonstrated that the CC chemokine receptor-7 (CCR7) ligands 6Ckine and macrophage inflammatory protein (MIP)-3β are selective chemoattractants for MHC class IIhigh B7-2high bone marrow-derived dendritic cells at a potency 1000-fold higher than their known activity on naive T cells.
Journal ArticleDOI
Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment.
TL;DR: It is shown that localized inflammation resulted in an increased binding of monocytes to perifollicular high endothelial venules (HEVs) of lymph nodes draining a local inflammatory site and that inflammation-induced MIG expression by HEVs can mediate monocyte recruitment.