S
Susan V. Booker
Researcher at Johns Hopkins University
Publications - 33
Citations - 9273
Susan V. Booker is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Familial adenomatous polyposis & Adenomatous polyposis coli. The author has an hindex of 29, co-authored 33 publications receiving 8969 citations. Previous affiliations of Susan V. Booker include Utah State University.
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Journal ArticleDOI
Treatment of Colonic and Rectal Adenomas with Sulindac in Familial Adenomatous Polyposis
Francis M. Giardiello,Stanley R. Hamilton,Anne J. Krush,Steven Piantadosi,Linda M. Hylind,Paul Celano,Susan V. Booker,C. Rahj Robinson,G. Johan A. Offerhaus +8 more
TL;DR: Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and it is unlikely to replace colectomy as primary therapy.
Journal ArticleDOI
Very High Risk of Cancer in Familial Peutz—Jeghers Syndrome
Francis M. Giardiello,Jill D. Brensinger,Anne C. Tersmette,Steven N. Goodman,Gloria M. Petersen,Susan V. Booker,Marcia Cruz-Correa,Johan Offerhaus +7 more
TL;DR: Patients with Peutz-Jeghers syndrome are at very high relative and absolute risk for gastrointestinal and nongastrointestinal cancers.
Journal ArticleDOI
The Molecular Basis of Turcot's Syndrome
Stanley R. Hamilton,Bo Liu,Ramon Parsons,Nickolas Papadopoulos,Jin Jen,Steven M. Powell,Anne J. Krush,Theresa Berk,Zane Cohen,Bernard Têtu,Peter C. Burger,Patricia A. Wood,Fowzia Taqi,Susan V. Booker,Gloria M. Petersen,G. Johan A. Offerhaus,Anne C. Tersmette,Francis M. Giardiello,Bert Vogelstein,Kenneth W. Kinzler +19 more
TL;DR: The association between brain tumors and multiple colorectal adenomas can result from two distinct types of germ-line defects: mutation of the APC gene or mutation of a mismatch-repair gene.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
Journal ArticleDOI
The risk of upper gastrointestinal cancer in familial adenomatous polyposis
G. Johan A. Offerhaus,Francis M. Giardiello,Anne J. Krush,Susan V. Booker,Anne C. Tersmette,N.Christopher Kelley,Stanley R. Hamilton +6 more
TL;DR: In this paper, the incidence rate of upper gastrointestinal cancer in patients with familial adenomatous polyposis in The Johns Hopkins Registry was compared with the rate of the general population through person-year analysis with adjustment for demographics.