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Susanne K. Kjaer

Researcher at University of Copenhagen

Publications -  674
Citations -  41997

Susanne K. Kjaer is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Population & Cancer. The author has an hindex of 90, co-authored 636 publications receiving 36979 citations. Previous affiliations of Susanne K. Kjaer include Copenhagen University Hospital & McGill University.

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Chapter 5: Updating the natural history of HPV and anogenital cancer.

TL;DR: The major steps in cervical carcinogenesis include infection of the metaplastic epithelium of the cervical transformation zone with one or more of the 12-18 carcinogenic types of human papillomavirus (HPV) infection, viral persistence, clonal progression of the persistently-infected epithelia to cervical precancer, and invasion.
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Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study

TL;DR: Infection with human papillomavirus precedes the development of low and high grade squamous intraepithelial lesions and for high grade lesions the risk is greatest in women positive for the same type of HPV on repeated testing.
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Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial.

TL;DR: Quadrivalent HPV vaccine provided sustained protection against low grade lesions attributable to vaccine HPV types and a substantial reduction in the burden of these diseases through 42 months of follow-up.