T
Tad S. Sonstegard
Researcher at Agricultural Research Service
Publications - 261
Citations - 20034
Tad S. Sonstegard is an academic researcher from Agricultural Research Service. The author has contributed to research in topics: Population & Genome. The author has an hindex of 64, co-authored 249 publications receiving 17635 citations. Previous affiliations of Tad S. Sonstegard include University of Maryland, College Park & Bhabha Atomic Research Centre.
Papers
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Book ChapterDOI
How bioinformatics enables livestock applied sciences in the genomic era
José Fernando Garcia,Adriana Santana do Carmo,Yuri Tani Utsunomiya,Haroldo H. R. Neves,Roberto Carvalheiro,Curtis P. Van Tassell,Tad S. Sonstegard,Marcos Vinícius Gualberto Barbosa da Silva +7 more
TL;DR: This review paper presents the three main approaches currently used in livestock genomic sciences where the bioinfomatics plays a critical role, named as Genomic Selection, Genome Wide Association Study (GWAS) and Signatures of Selection (SS).
Journal ArticleDOI
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle
Wai Yee Low,Benjamin D. Rosen,Yang Ren,Derek M. Bickhart,Thu-Hien To,Fergal J. Martin,Konstantinos Billis,Tad S. Sonstegard,Shawn T. Sullivan,Stefan Hiendleder,Michael P. Heaton,Timothy P. L. Smith +11 more
TL;DR: In this paper , the authors report the first gaur reference genome and identify three biological pathways including lysozyme activity, proton transmembrane transporter activity, and oxygen transport with significant changes in gene copy number in gaur compared to other mammals.
Journal ArticleDOI
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle
Wai Yee Low,Benjamin D. Rosen,Yang Ren,Derek M. Bickhart,Thu-Hien To,Fergal J. Martin,Konstantinos Billis,Tad S. Sonstegard,Shawn T. Sullivan,Stefan Hiendleder,Michael P. Heaton,Timothy P. L. Smith +11 more
TL;DR: In this article , the authors report the first gaur reference genome and identify three biological pathways including lysozyme activity, proton transmembrane transporter activity, and oxygen transport with significant changes in gene copy number in gaur compared to other mammals.
Approaches taken, progress made, and enhanced utility of long read-based goat, swine, cattle and sheep reference genomes
Timothy P. L. Smith,Sergey Koren,Adam M. Phillippy,Derek M. Bickhart,Benjamin D. Rosen,Kim C. Worley,Steven G. Schroeder,Brian L. Saye,Ivan Liachko,Shawn Sullivan,Joshua N. Burton,Alex Hastie,Tad S. Sonstegard,Christy M. Kelley,Alan Archibald,Alan Archibald,Mick Watson,Mick Watson,Richard E. Green,Jason Chin,Dan J. Nonneman,Gary A. Rohrer,Christopher K. Tuggle,Habio Liu,Daniel C. Ciobanu,Juan F. Medrano,Aleksey V. Zimin,Sebastian J. Schultheiss,Darren E. Hagen,Christine G. Elsik,Brian P. Dalrymple,James Kijas,Noelle E. Cockett,Michael P. Heaton +33 more
Posted ContentDOI
First gene-edited calf with reduced susceptibility to a major viral pathogen
Aspen M. Workman,Michael P. Heaton,Brian L. Vander Ley,Dennis A. Webster,L. Sherry,Sabreena A Larson,Theodore S. Kalbfleisch,Gregory P. Harhay,Erin E. Jobman,Daniel F. Carlson,Tad S. Sonstegard +10 more
TL;DR: The authors used CRISPR-mediated homology-directed repair and somatic cell nuclear transfer to produce a live calf with a six amino acid substitution in the BVDV binding domain of bovine CD46.