T
Takayo Sasaki
Researcher at Florida State University
Publications - 43
Citations - 2117
Takayo Sasaki is an academic researcher from Florida State University. The author has contributed to research in topics: Replication timing & Genome. The author has an hindex of 18, co-authored 40 publications receiving 1540 citations. Previous affiliations of Takayo Sasaki include Hiroshima University & State University of New York Upstate Medical University.
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Journal ArticleDOI
An encyclopedia of mouse DNA elements (Mouse ENCODE)
John A. Stamatoyannopoulos,Michael Snyder,Ross C. Hardison,Bing Ren,Thomas R. Gingeras,David M. Gilbert,Mark Groudine,M. A. Bender,Rajinder Kaul,Theresa K. Canfield,Erica Giste,Audra K. Johnson,Mia Zhang,Gayathri Balasundaram,Rachel Byron,Vaughan Roach,Peter J. Sabo,Richard Sandstrom,A Sandra Stehling,Robert E. Thurman,Sherman M. Weissman,Philip Cayting,Manoj Hariharan,Jin Lian,Yong Cheng,Stephen G. Landt,Zhihai Ma,Barbara J. Wold,Job Dekker,Gregory E. Crawford,Cheryl A. Keller,Weisheng Wu,Christopher T. Morrissey,Swathi Ashok Kumar,Tejaswini Mishra,Deepti Jain,Marta Byrska-Bishop,Daniel Blankenberg,Bryan R. Lajoie,Gaurav Jain,Amartya Sanyal,Kaun-Bei Chen,Olgert Denas,James Taylor,Gerd A. Blobel,Mitchell J. Weiss,Max Pimkin,Wulan Deng,Georgi K. Marinov,Brian A. Williams,Katherine I. Fisher-Aylor,Gilberto DeSalvo,Anthony Kiralusha,Diane Trout,Henry Amrhein,Ali Mortazavi,Lee Edsall,David McCleary,Samantha Kuan,Yin Shen,Feng Yue,Zhen Ye,Carrie A. Davis,Chris Zaleski,Sonali Jha,Chenghai Xue,Alexander Dobin,Wei Lin,Meagan Fastuca,Huaien Wang,Roderic Guigó,Sarah Djebali,Julien Lagarde,Tyrone Ryba,Takayo Sasaki,Venkat S. Malladi,Melissa S. Cline,Vanessa M. Kirkup,Katrina Learned,Kate R. Rosenbloom,W. James Kent,Elise A. Feingold,Peter J. Good,Michael J. Pazin,Rebecca F. Lowdon,Leslie B Adams +85 more
TL;DR: The Mouse E NCODE Consortium is applying the same experimental pipelines developed for human ENCODE to annotate the mouse genome to enable a broad range of mouse genomics efforts.
Journal ArticleDOI
Integrative detection and analysis of structural variation in cancer genomes
Jesse R. Dixon,Jie Xu,Vishnu Dileep,Ye Zhan,Fan Song,Victoria T. Le,Galip Gürkan Yardımcı,Abhijit Chakraborty,Darrin V. Bann,Yanli Wang,Royden A. Clark,Lijun Zhang,Hongbo Yang,Tingting Liu,Sriranga Iyyanki,Lin An,Christopher Pool,Takayo Sasaki,Juan Carlos Rivera-Mulia,Hakan Ozadam,Bryan R. Lajoie,Rajinder Kaul,Michael Buckley,Kristen Lee,Morgan Diegel,Dubravka Pezic,Christina Ernst,Suzana Hadjur,Duncan T. Odom,Duncan T. Odom,John A. Stamatoyannopoulos,James R. Broach,Ross C. Hardison,Ferhat Ay,Ferhat Ay,William Stafford Noble,Job Dekker,Job Dekker,David M. Gilbert,Feng Yue +39 more
TL;DR: An integrative framework for identifying structural variants (SVs) in cancer that applies optical mapping, Hi-C, and whole-genome sequencing is presented and finds SVs affecting distal regulatory sequences, DNA replication, and three-dimensional chromatin structure.
Journal ArticleDOI
Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells
Juan Carlos Rivera-Mulia,Quinton Buckley,Takayo Sasaki,Jared Zimmerman,Ruth Didier,Kristopher L. Nazor,Jeanne F. Loring,Zheng Lian,Sherman M. Weissman,Allan J. Robins,Thomas C. Schulz,Laura Menendez,Michael Kulik,Stephen Dalton,Haitham Gabr,Tamer Kahveci,David M. Gilbert +16 more
TL;DR: Interestingly, transcriptome data revealed that the well-accepted correlation between early replication and transcriptional activity was restricted to RT-constitutive genes, whereas two-thirds of the genes that switched RT during differentiation were strongly expressed when late replicating in one or more cell types.
Journal ArticleDOI
Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq.
Claire Marchal,Takayo Sasaki,Daniel L. Vera,Korey A. Wilson,Jiao Sima,Juan Carlos Rivera-Mulia,Claudia Trevilla-Garcia,Coralin Nogues,Ebtesam Nafie,David M. Gilbert +9 more
TL;DR: E/L Repli-seq is a rapid, robust and relatively inexpensive protocol for analyzing RT by next-generation sequencing (NGS), allowing genome-wide assessment of how cellular processes are linked to RT.
Journal ArticleDOI
The many faces of the origin recognition complex.
Takayo Sasaki,David M. Gilbert +1 more
TL;DR: The hetero-hexameric origin recognition complex is well known for its separable roles in DNA replication and heterochromatin assembly, but recent findings directly link ORC to sister chromatin cohesion, cytokinesis and neural dendritic branching.