http://depa.fquim.unam.mx/amyd/archivero/Modeling-CrusRamirezyVargasPavonyJimenezSolorzano_11276.pdf

Modeling and comparison of dissolution profiles.

Overview of membrane science and technology membrane transport theory membrane and modules concentration polarization reverse osmosis ultrafiltration microfiltration gas separation pervaporation ion exchange membrane processes - electrodialysis carrier facilitated transport medical applications of membranes other membranes processed.

Membrane Technology and Applications

A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC).

Recent advances on chitosan-based micro- and nanoparticles in drug delivery.

A number of theoretical relations dealing with diffusion through heterogeneous barriers are presented and discussed. These are expected to be useful in predicting barrier behavior in formulations such as pharmaceutical and particularly protective ointments and films. A relationship has been derived which expresses the effective permeability constant, Pm, of a two phase mixture as a function of the volume fraction and the permeability of each phase. The effect of the shape of the particles on Pm is also considered. Where data are available, agreement with theory is satisfactory. The nonstationary state behavior of a two phase heterogeneous barrier is discussed in relation to the diffusion coefficient, partition coefficient, the volume fraction, and the particle size associated with each phase. It is shown that the effectiveness of one heterogeneous barrier may be greater than another for a given time of exposure while for a longer time of exposure the reverse may be the case. The effect of a “skin” or a coat of a third phase on the internal phase particle has also been examined. Finally, the situation in which simultaneous diffusion and absorption occur is discussed and an expression for the lag time has been derived for this case.

Theoretical analysis of diffusional movement through heterogeneous barriers

N-substituted 1-cyanobenz[f]isoindole: evaluation of fluorescence efficiencies of a new fluorogenic label for primary amines and amino acids.

Rates of hydrolysis of carbamate and carbonate esters in alkaline solution

Multiple intermediates generate fluorophore-derived light in the oxalate/peroxide chemiluminescence system

Thermodynamic group contributions from ion pair extraction equilibriums for use in the prediction of partition coefficients. Correlation of surface area with group contributions

Takeru Higuchi

Papers

Theoretical analysis of diffusional movement through heterogeneous barriers

N-substituted 1-cyanobenz[f]isoindole: evaluation of fluorescence efficiencies of a new fluorogenic label for primary amines and amino acids.

Rates of hydrolysis of carbamate and carbonate esters in alkaline solution

Multiple intermediates generate fluorophore-derived light in the oxalate/peroxide chemiluminescence system

Thermodynamic group contributions from ion pair extraction equilibriums for use in the prediction of partition coefficients. Correlation of surface area with group contributions