http://depa.fquim.unam.mx/amyd/archivero/Modeling-CrusRamirezyVargasPavonyJimenezSolorzano_11276.pdf

Modeling and comparison of dissolution profiles.

Overview of membrane science and technology membrane transport theory membrane and modules concentration polarization reverse osmosis ultrafiltration microfiltration gas separation pervaporation ion exchange membrane processes - electrodialysis carrier facilitated transport medical applications of membranes other membranes processed.

Membrane Technology and Applications

A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC).

Recent advances on chitosan-based micro- and nanoparticles in drug delivery.

Influence of self-association on the solubility of phenol in isooctane and cyclohexane

A new approach to possible preservation of drugs undergoing hydrolytic degradation is presented. It is shown that the rate of hydrolysis of benzocaine in aqueous solution can be substantially inhibited by addition of caffeine which has previously been shown to complex with this drug. Presence of two and one‐half per cent of caffeine in the system resulted in reduction of the hydrolytic rate to less than one‐fifth of that in absence of the xanthine. Mathematical analysis of the results obtained indicates that the complexed form of the drug does not undergo, surprisingly, any perceptible cleavage at the ester linkage.

Inhibition of Hydrolysis of Esters in Solution by Formation of Complexes I

Ion-Pair Extraction of Pharmaceutical Amines II: Extraction Profile of Chlorpheniramine

The permeability of protective barriers containing adsorbent type fillers has been studied. It has been shown that the time for the nonstationary state permeation of these barriers can be significantly increased by the incorporation of small quantities of an active filler into the ointment base. The theoretical considerations of permeation through filled ointments have been presented with particular emphasis placed on the theory pertaining to barriers containing a filler with a high affinity for the penetrant. An equation relating the lag time to the concentration and maximum adsorptive capacity of this type filler and to the initial concentration of the chemical agent has been derived and verified by experimental procedures.

Investigation and Development of Protective Ointments IV.: The influence of active fillers on the permeability of semisolids

A method of assaying primary amines or cyanide is disclosed. The process is carried out by reacting a substituted or unsubstituted naphthalene-2,3-dicarboxaldehyde or o-phthalaldehyde, reactive with primary amines and cyanide, with cyanide ions and at least one primary amine to form an adduct amenable to fluorometric or electrochemical assaying techniques. The adduct is then fluorometrically or electrochemically assayed. Also disclosed are 1-cyano-benz[f]isoindole adducts.

Takeru Higuchi

Papers

Influence of self-association on the solubility of phenol in isooctane and cyclohexane

Inhibition of Hydrolysis of Esters in Solution by Formation of Complexes I

Ion-Pair Extraction of Pharmaceutical Amines II: Extraction Profile of Chlorpheniramine

Investigation and Development of Protective Ointments IV.: The influence of active fillers on the permeability of semisolids

Assaying method for primary amines using aromatic dialdehydes