T
Taoufik Nedjadi
Researcher at University of Liverpool
Publications - 12
Citations - 635
Taoufik Nedjadi is an academic researcher from University of Liverpool. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 9, co-authored 11 publications receiving 552 citations. Previous affiliations of Taoufik Nedjadi include Royal Liverpool University Hospital.
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Journal ArticleDOI
Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy
Adam Lister,Taoufik Nedjadi,Neil R. Kitteringham,Fiona Campbell,Eithne Costello,Bryony H. Lloyd,Ian M. Copple,Samantha J. Williams,Andrew Owen,John P. Neoptolemos,Christopher E. Goldring,B. Kevin Park +11 more
TL;DR: Expression of Nrf2 is up-regulated in pancreatic cancer cell lines and ductal adenocarcinomas, which may reflect a greater intrinsic capacity of these cells to respond to stress signals and resist chemotherapeutic interventions.
Journal ArticleDOI
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility
Taoufik Nedjadi,Neil R. Kitteringham,Fiona Campbell,Rosalind E. Jenkins,Brian Kevin Park,Pilar Navarro,Felicity Ashcroft,Alexei V. Tepikin,John P. Neoptolemos,Eithne Costello +9 more
TL;DR: Findings point towards a functional role for S100A6 that may help explain the link between S 100A6 expression in pancreatic cancer and aggressive disease.
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Low molecular weight heat shock protein hsp27 is a prognostic indicator in rectal cancer but not colon cancer.
Elizabeth M Tweedle,Ilyas Khattak,Chin Wee Ang,Taoufik Nedjadi,Rosalind E. Jenkins,B. Kevin Park,Helen Kalirai,Andy Dodson,Bahram Azadeh,Monica Terlizzo,Heike I. Grabsch,Wolfram Mueller,Sun Myint,Peter A. Clark,Helen Wong,William Greenhalf,John P. Neoptolemos,Paul Rooney,Eithne Costello +18 more
TL;DR: In a large cohort of patients with a poor prognosis, HSP27 is an independent marker of poor outcome in rectal cancer; its expression is not altered by neoadjuvant radiotherapy.
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Multifunctional Fe3O4 nanoparticles for targeted bi-modal imaging of pancreatic cancer
Cristina Ioana Olariu,Humphrey H. P. Yiu,Laurent Bouffier,Taoufik Nedjadi,Eithne Costello,Steven Williams,Christopher Halloran,Matthew J. Rosseinsky +7 more
TL;DR: These bifunctionalized nanoparticles target and then undergo facilitated uptake into pancreatic cancer cells (Panc-1) in a time course-monitored controlled study and is a candidate for further development as a multi-modular imaging, diagnostic and delivery tool.
Journal ArticleDOI
The expression of S100A8 in pancreatic cancer‐associated monocytes is associated with the Smad4 status of pancreatic cancer cells
Adnan Sheikh,D. Vimalachandran,Christopher C. Thompson,Rosalind E. Jenkins,Taoufik Nedjadi,Ali Shekouh,Fiona Campbell,Andrew Dodson,Wendy Prime,Tatjana Crnogorac-Jurcevic,Nicholas R. Lemoine,Eithne Costello +11 more
TL;DR: This study provides an extensive analysis of S 100A8 and S100A9 in pancreatic disease and highlights a potentially important relationship between pancreatic cancer cells and their surrounding microenvironment.