T
Ted Trimble
Researcher at National Institutes of Health
Publications - 11
Citations - 1214
Ted Trimble is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cervical cancer & Palliative care. The author has an hindex of 6, co-authored 11 publications receiving 1034 citations.
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Journal ArticleDOI
Reducing Uncertainties About the Effects of Chemoradiotherapy for Cervical Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 18 Randomized Trials
Claire L Vale,Jayne F. Tierney,Lesley A. Stewart,Mark F. Brady,Ketayun A. Dinshaw,Anders Jakobsen,Mahesh K. B. Parmar,Gillian Thomas,Ted Trimble,David S. Alberts,Hongwei Chen,Slobodan Cikaric,Patricia J. Eifel,Melahat Garipagaoglu,Henry M. Keys,Nermina Kantardzic,Punita Lal,Rachelle Lanciano,Felix Leborgne,Vicharn Lorvidhaya,Hiroshi Onishi,Robert Pearcey,E Pras,Kenneth B. Roberts,Peter G. Rose,Charles W. Whitney +25 more
TL;DR: These results endorse the recommendations of the NCI alert, but also demonstrate their applicability to all women and a benefit of non-platinum-based chemoradiotherapy.
Journal Article
Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: individual patient data meta-analysis
David S. Alberts,Mark F. Brady,S Cikaric,H Chen,Ketayun A. Dinshaw,Patricia J. Eifel,M Garipagaoglu,Anders Jakobsen,N Kantardzic,Henry M. Keys,Punita Lal,Rachelle Lanciano,F Leborgne,Lorvidhaya,H Onishi,M. K. B. Parmar,Robert Pearcey,E Pras,Kenneth B. Roberts,Peter G. Rose,Lesley A. Stewart,Jayne F. Tierney,Gillian Thomas,Ted Trimble,Claire L Vale,Charles W. Whitney +25 more
TL;DR: A meta-analysis seeking updated individual patient data (IPD) from all randomised controlled trials (RCTs) to assess the effect of chemoradiotherapy on all outcomes endorsed the recommendations of the NCI alert, but also demonstrated their applicability to all women and a benefit of non-platinum based cheMoradiotherapy.
Journal ArticleDOI
Clinical trial designs for rare diseases: Studies developed and discussed by the International Rare Cancers Initiative
Jan Bogaerts,Matthew R. Sydes,Nicola Keat,Andrea McConnell,Al B. Benson,Alan L. Ho,Arnaud Roth,Catherine Fortpied,Cathy Eng,Clare Peckitt,Corneel Coens,Curtis A. Pettaway,Dirk Arnold,Emma Hall,Ernie Marshall,Francesco Sclafani,Helen Hatcher,Helena M. Earl,Isabelle Ray-Coquard,James Paul,Jean-Yves Blay,Jeremy Whelan,K. S. Panageas,Keith Wheatley,Kevin J. Harrington,Lisa Licitra,Lucinda Billingham,Martee L. Hensley,Martin G. McCabe,Poulam M. Patel,Richard D. Carvajal,Richard H. Wilson,Rob Glynne-Jones,Rob Mcwilliams,Serge Leyvraz,Sheela Rao,Steve Nicholson,Virginia L. Filiaci,Anastassia Negrouk,Denis Lacombe,Elisabeth Dupont,Iris Pauporte,John J. Welch,Kate Law,Ted Trimble,Matthew T. Seymour +45 more
TL;DR: The IRCI trials are each presented to exemplify possible approaches to designing credible trials in rare cancers and to consider these for use in future trials and understand the choices made for each design.
Journal ArticleDOI
International rare cancers initiative.
Nicola Keat,Kate Law,Matthew T. Seymour,John J. Welch,Ted Trimble,Denis Lascombe,Anastassia Negrouk +6 more
Journal ArticleDOI
Ending cervical cancer: A call to action.
Sanchia Aranda,Seth Berkley,Sally Cowal,Mark Dybul,Timothy G Evans,Katja Iversen,Matshidiso Moeti,Babatunde Osotimehin,Stefan Peterson,Peter Piot,C. N. Purandare,Michel Sidibé,Ted Trimble,Vivien Tsu +13 more
TL;DR: If all countries with a substantial burden of disease introduce the vaccine nationally, the authors can protect the vast majority of women and girls most at risk of cervical cancer and reduce incidence and mortality worldwide to the very low rates found in wealthier countries.