T
Thomas M. Badger
Researcher at University of Arkansas for Medical Sciences
Publications - 305
Citations - 13313
Thomas M. Badger is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Soy protein & Offspring. The author has an hindex of 63, co-authored 299 publications receiving 12304 citations. Previous affiliations of Thomas M. Badger include University of Arkansas & United States Department of Agriculture.
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Journal ArticleDOI
Isoflavone conjugates are underestimated in tissues using enzymatic hydrolysis.
Liwei Gu,Myriam Laly,Hebron C. Chang,Ronald L. Prior,Nianbai Fang,Martin J. J. Ronis,Thomas M. Badger +6 more
TL;DR: It is demonstrated that soy isoflavones distribute in a wide variety of tissues as aglycon and conjugates and the concentrations of is oflavone aglycons, which are thought to be the bioactive molecules, are in the 0.2-0.25 nmol/g range, far below the concentrations required for most in vitro effects of genistein or daidzein.
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Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective.
Meghan L. Ruebel,Matthew Cotter,Clark R. Sims,Dean M. Moutos,Thomas M. Badger,Mario A. Cleves,Kartik Shankar,Aline Andres +7 more
TL;DR: Findings provide evidence for the significant influence of body composition on oocyte transcript abundance in women undergoing hormonal induction to retrieve oocytes and identify the potential for maternal diet to influence oocyte gene expression.
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Restoration of regenerative osteoblastogenesis in aged mice: modulation of TNF.
Elizabeth C. Wahl,James Aronson,Lichu Liu,John L. Fowlkes,Kathryn M. Thrailkill,Robert C. Bunn,Robert A. Skinner,Mike J. Miller,Gael Cockrell,Lindsey M. Clark,Yang Ou,Carlos M. Isales,Thomas M. Badger,Martin J. J. Ronis,John E. Sims,Charles K. Lumpkin +15 more
TL;DR: It is shown that aged‐related deficits in direct bone formation can be restored to young mice by treatment with TNF blockers and that the cyclin‐dependent kinase inhibitor p21 is a candidate for mediation of the osteoinhibitory effects of TNF.
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Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats.
Jin-Ran Chen,Oxana P. Lazarenko,Kartik Shankar,Michael L. Blackburn,Charles K. Lumpkin,Thomas M. Badger,Martin J. J. Ronis +6 more
TL;DR: In a rat model in which cycling females were infused intragastrically with EtOH-containing liquid diets, EtOH significantly decreased bone formation and stimulated osteoblast-dependent osteoclast differentiation, and these effects were reversed by exogenous 17-β-estradiol coadministration.
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Selective Failure of Androgens to Regulate Follicle Stimulating Hormone β Messenger Ribonucleic Acid Levels in the Male Rat
TL;DR: In the male rat, estrogens negatively regulate all three gonadotropin subunit mRNA levels while androgens negative regulate LH beta and alpha-subunit but fail to suppress FSH beta mRNAs, demonstrating a relative lack of negative regulation of FSHbeta mRNA levels by androgens.