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Thomas M. Badger

Researcher at University of Arkansas for Medical Sciences

Publications -  305
Citations -  13313

Thomas M. Badger is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Soy protein & Offspring. The author has an hindex of 63, co-authored 299 publications receiving 12304 citations. Previous affiliations of Thomas M. Badger include University of Arkansas & United States Department of Agriculture.

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Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition.

Martin J. J. Ronis, +9 more
- 01 Sep 2005 - 
TL;DR: The data suggest that ethanol-induced oxidative stress can contribute to inflammation and liver injury even in the absence of Kupffer cell activation by endotoxemia.
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Blueberries reduce pro‐inflammatory cytokine TNF‐α and IL‐6 production in mouse macrophages by inhibiting NF‐κB activation and the MAPK pathway

Cheng-Hui Xie, +5 more
- 01 Oct 2011 - 
TL;DR: Blueberries (BB) significantly inhibited LPS-induced mRNA expression and protein levels of TNF-α and IL-6 and inhibited the phosphorylation of IκB, NF-κB p65, MAPK p38 and JNK, all of these are important signaling pathways involved in the production of T NF- α andIL-6.
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Dietary Saturated Fat Reduces Alcoholic Hepatotoxicity in Rats by Altering Fatty Acid Metabolism and Membrane Composition

Martin J. J. Ronis, +4 more
- 01 Apr 2004 - 
TL;DR: Saturated fat protected rats from alcoholic liver disease in a dose-responsive fashion and reduced alcoholic steatosis was associated with reduced fatty acid synthesis in combination with increased CYP4A-catalyzed fatty acid oxidation and effects on lipid export.
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Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high.

Thomas M. Badger, +3 more
- 15 Feb 1993 - 
TL;DR: It is demonstrated for the first time that CYP 2E1 induction by chronic ethanol is associated with increased CYP2E1 gene transcription and is independent of gonadal factors.
Journal Article

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat.

Thomas M. Badger, +9 more
- 01 Jan 1993 - 
TL;DR: The results suggest that the reduced CYP 2C11 activities, apoprotein levels and steady-state mRNA levels during chronic alcohol exposure are causally related to the alterations in GH secretion.