T
Tim Magnus
Researcher at University of Hamburg
Publications - 154
Citations - 7001
Tim Magnus is an academic researcher from University of Hamburg. The author has contributed to research in topics: Microglia & Inflammation. The author has an hindex of 38, co-authored 133 publications receiving 5338 citations. Previous affiliations of Tim Magnus include Hamburg University of Technology & Eppendorf (Germany).
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Journal ArticleDOI
Dimethylarginine Dimethylaminohydrolase-1 Transgenic Mice Are Not Protected from Ischemic Stroke
Frank Leypoldt,Chi-Un Choe,Mathias Gelderblom,Eike-Christin von Leitner,Dorothee Atzler,Edzard Schwedhelm,Christian Gerloff,Karsten Sydow,Rainer H. Böger,Tim Magnus +9 more
TL;DR: This study demonstrates that hDDAH-1 transgenic mice are not protected from ischemic cerebral tissue damage in tMCAO, and this lack of protection is due to high basal cerebral DDAH activity, which is not further increasable by transgenic overexpression of D DAH.
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Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.
Mathias Gelderblom,Tristan Daehn,Benjamin Schattling,Peter Ludewig,Christian Bernreuther,Priyadharshini Arunachalam,Jakob Matschke,Markus Glatzel,Christian Gerloff,Manuel A. Friese,Tim Magnus +10 more
TL;DR: Plasma NSE is a valid and simple experimental biomarker that allows quantifying the degree of neuronal injury in a non-invasive approach and even predicted the onset of EAE, before clinical signs were recordable.
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Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid.
Milani Deb-Chatterji,Simon Schuster,Vivien Haeussler,Christian Gerloff,Götz Thomalla,Tim Magnus +5 more
TL;DR: This short review summarizes the current procedures within the diagnostic process and aims to illustrate its difficulties and challenges and highlights emerging biomarkers in the cerebrospinal fluid and peripheral venous blood as well as novel potential imaging tools that may corroborate the diagnosis.
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Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy
Larissa Jank,Carolina Pinto-Espinoza,Yinghui Duan,Friedrich Koch-Nolte,Tim Magnus,Björn Rissiek +5 more
TL;DR: Recent findings on Nbs in preclinical stroke models are summarized and a perspective on the design of innovative Nb-based treatment protocols to complement and improve stroke therapy is provided.
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Neuroradiologic Characteristics of Primary Angiitis of the Central Nervous System According to the Affected Vessel Size
Christian J. Thaler,Ann-Katrin Kaufmann-Bühler,Tserenchunt Gansukh,Amarjargal Gansukh,Simon Schuster,Henrike Bachmann,Götz Thomalla,Tim Magnus,Jakob Matschke,Jens Fiehler,Susanne Siemonsen +10 more
TL;DR: The results emphasize the importance of MRI/MRA in the diagnosis process of PACNS and differentiate between small and medium/large vessel PACNS since results in MRI, digital subtraction angiography and brain biopsy may differ immensely.