T
Tinri Aegerter-Wilmsen
Researcher at University of Zurich
Publications - 18
Citations - 1399
Tinri Aegerter-Wilmsen is an academic researcher from University of Zurich. The author has contributed to research in topics: Fin & Imaginal disc. The author has an hindex of 13, co-authored 18 publications receiving 1202 citations. Previous affiliations of Tinri Aegerter-Wilmsen include Wageningen University and Research Centre.
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Journal ArticleDOI
MorphoGraphX: A platform for quantifying morphogenesis in 4D
Pierre Barbier de Reuille,Anne-Lise Routier-Kierzkowska,Daniel Kierzkowski,George W. Bassel,Thierry Schüpbach,Gerardo Tauriello,Namrata Bajpai,Sören Strauss,Alain Weber,Annamaria Kiss,Agata Burian,Agata Burian,Hugo Hofhuis,Aleksandra Sapala,Marcin Lipowczan,Maria B. Heimlicher,Sarah Robinson,Emmanuelle Bayer,Konrad Basler,Petros Koumoutsakos,Adrienne H. K. Roeder,Tinri Aegerter-Wilmsen,Naomi Nakayama,Naomi Nakayama,Miltos Tsiantis,Angela Hay,Dorota Kwiatkowska,Ioannis Xenarios,Cris Kuhlemeier,Richard S. Smith,Richard S. Smith +30 more
TL;DR: MorphoGraphX is a software that bridges the gap by working directly with curved surface images extracted from 3D data, and has developed algorithms to operate on curved surfaces, such as cell segmentation, lineage tracking and fluorescence signal quantification.
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Model for the regulation of size in the wing imaginal disc of Drosophila.
TL;DR: This work presents a model for the control of growth in the wing imaginal disc of Drosophila, which can account for the uniform occurrence and termination of growth, and shows that the model indeed yields uniform growth.
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Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues
Wade W. Sugden,Robert Meissner,Tinri Aegerter-Wilmsen,Roman Tsaryk,Roman Tsaryk,Elvin Leonard,Elvin Leonard,Jeroen Bussmann,Jeroen Bussmann,Mailin Julia Hamm,Mailin Julia Hamm,Wiebke Herzog,Wiebke Herzog,Yi Jin,Lars Jakobsson,Cornelia Denz,Arndt F. Siekmann,Arndt F. Siekmann +17 more
TL;DR: It is shown that during zebrafish embryonic development increases in flow, after an initial expansion of blood vessel diameters, eventually lead to vessel contraction, mediated via endothelial cell shape changes.
Journal ArticleDOI
Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size
Tinri Aegerter-Wilmsen,Maria B. Heimlicher,Alister C. Smith,Pierre Barbier de Reuille,Richard S. Smith,Christof M. Aegerter,Konrad Basler +6 more
TL;DR: A regulatory network is modeled that integrates the experimentally confirmed molecular interactions underlying other available models, leading to a size regulation mechanism that conceptually combines elements of existing models, and can be understood in terms of a compression gradient model.
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Exploring the effects of mechanical feedback on epithelial topology.
Tinri Aegerter-Wilmsen,Alister C. Smith,Alix J. Christen,Christof M. Aegerter,Christof M. Aegerter,Ernst Hafen,Konrad Basler +6 more
TL;DR: Interestingly, simulations of several theoretical scenarios showed a large decrease in rearrangements and elimination of cells, suggesting a possible growth regulation by mechanical force could have a function in releasing the mechanical stress that evolves when all cells have similar growth rates.