T
Tiziana Schioppa
Researcher at University of Brescia
Publications - 40
Citations - 6082
Tiziana Schioppa is an academic researcher from University of Brescia. The author has contributed to research in topics: Chemokine & Cytokine. The author has an hindex of 17, co-authored 32 publications receiving 5184 citations. Previous affiliations of Tiziana Schioppa include Humanitas University & Queen Mary University of London.
Papers
More filters
Journal ArticleDOI
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
TL;DR: Evidence is presented here supporting the view that TAM represent a unique and distinct M2-skewed myeloid population and are a potential target for anti-cancer therapy.
Journal ArticleDOI
Regulation of the chemokine receptor CXCR4 by hypoxia.
Tiziana Schioppa,Badarch Uranchimeg,Alessandra Saccani,Subhra K. Biswas,Andrea Doni,Annamaria Rapisarda,Sergio Bernasconi,Simona Saccani,Manuela Nebuloni,Luca Vago,Alberto Mantovani,Alberto Mantovani,Giovanni Melillo,Antonio Sica +13 more
TL;DR: It is described that oxygen availability is a determinant parameter in the setting of chemotactic responsiveness to stromal-derived factor 1 (CXCL12), and the Hyp–Hyp-inducible factor 1 α–CXCR4 pathway may regulate trafficking in and out of hypoxic tissue microenvironments.
Journal ArticleDOI
Role of tumor-associated macrophages in tumor progression and invasion.
TL;DR: Evidence supporting the view that TAM represent a unique and distinct M2-skewed myeloid population and a potential target of anti-cancer therapy is discussed.
Journal ArticleDOI
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)
Subhra K. Biswas,Lisa Gangi,Saki Paul,Tiziana Schioppa,Alessandra Saccani,Marina Sironi,Barbara Bottazzi,Andrea Doni,Bronte Vincenzo,Fabio Pasqualini,Luca Vago,Manuela Nebuloni,Alberto Mantovani,Antonio Sica +13 more
TL;DR: In this article, the gene expression profile of TAMs isolated from a murine fibrosarcoma in comparison with peritoneal macrophages (PECs) and myeloid suppressor cells (MSCs), using a cDNA microarray technology, was characterized.
Journal ArticleDOI
p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance
Alessandra Saccani,Tiziana Schioppa,Chiara Porta,Subhra K. Biswas,Manuela Nebuloni,Luca Vago,Barbara Bottazzi,Mario P. Colombo,Alberto Mantovani,Antonio Sica +9 more
TL;DR: It is reported that defective responsiveness of TAM from a murine fibrosarcoma and human ovarian carcinoma to M1 activation signals was associated with a massive nuclear localization of the p50 nuclear factor-kappaB (NF-kappB) inhibitory homodimer.