T
Todd A. Naumann
Researcher at National Center for Agricultural Utilization Research
Publications - 50
Citations - 1132
Todd A. Naumann is an academic researcher from National Center for Agricultural Utilization Research. The author has contributed to research in topics: Chitinase & Transposase. The author has an hindex of 18, co-authored 43 publications receiving 1003 citations. Previous affiliations of Todd A. Naumann include Pennsylvania State University & Agricultural Research Service.
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Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models.
Joshua A. Kritzer,Shusei Hamamichi,J. Michael McCaffery,Sandro Santagata,Sandro Santagata,Todd A. Naumann,Kim A. Caldwell,Guy A. Caldwell,Susan Lindquist +8 more
TL;DR: This work describes the first expressed library of head-to-tail cyclic peptides in yeast, which specifically reduce the toxicity of human α-synuclein and prevents dopaminergic neuron loss in an established Caenorhabditis elegans Parkinson’s model.
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cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase.
TL;DR: It was determined that a single isoform accounts for both soluble and membrane-bound and nuclear and cytosolic-localized enzyme in macrophages and BMMC and raises questions about the role of 5-lipoxygenase and leukotrienes within the nucleus.
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Identification of a Chitinase-modifying Protein from Fusarium verticillioides TRUNCATION OF A HOST RESISTANCE PROTEIN BY A FUNGALYSIN METALLOPROTEASE
TL;DR: This is the first report of a fungalysin that targets a nonstructural host protein and the first to implicate this class of virulence-related proteases in plant disease.
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Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease
Lin Cheng,Todd A. Naumann,Alexander R. Horswill,Sue Jean Hong,Bryan J. Venters,John W. Tomsho,Stephen J. Benkovic,Kenneth C. Keiler +7 more
TL;DR: Fluorescence activated cell sorting was used in conjunction with a fluorescent reporter to isolate cyclic peptides that inhibit the proteolysis of tmRNA‐tagged proteins in Escherichia coli.
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Chromosomal Deletion Formation System Based on Tn5 Double Transposition: Use For Making Minimal Genomes and Essential Gene Analysis
TL;DR: The use of specialized transposons (Tn5 derivatives) to create deletions in the Escherichia coli K-12 chromosome provides a robust technology for identifying essential and dispensable genes.