T
Tomotaka Ugai
Researcher at Harvard University
Publications - 112
Citations - 1353
Tomotaka Ugai is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 83 publications receiving 640 citations. Previous affiliations of Tomotaka Ugai include Jichi Medical University & Brigham and Women's Hospital.
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Journal ArticleDOI
Rising incidence of early-onset colorectal cancer - a call to action.
Naohiko Akimoto,Tomotaka Ugai,Tomotaka Ugai,Rong Zhong,Rong Zhong,Rong Zhong,Tsuyoshi Hamada,Kenji Fujiyoshi,Kenji Fujiyoshi,Marios Giannakis,Kana Wu,Yin Cao,Kimmie Ng,Shuji Ogino +13 more
TL;DR: The authors review the current epidemiological, clinical, pathological and molecular understanding of early-onset colorectal cancer that occurs in patients ≥50 years of age, drawing contrasts with later-ONSet CRC.
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The Prognostic Role of Macrophage Polarization in the Colorectal Cancer Microenvironment.
Juha P. Väyrynen,Juha P. Väyrynen,Juha P. Väyrynen,Koichiro Haruki,Koichiro Haruki,Mai Chan Lau,Sara A. Väyrynen,Rong Zhong,Andressa Dias Costa,Jennifer Borowsky,Melissa Zhao,Kenji Fujiyoshi,Kota Arima,Tyler S. Twombly,Junko Kishikawa,Simeng Gu,Saina Aminmozaffari,Shanshan Shi,Yoshifumi Baba,Naohiko Akimoto,Tomotaka Ugai,Tomotaka Ugai,Annacarolina da Silva,Jennifer L. Guerriero,Jennifer L. Guerriero,Mingyang Song,Kana Wu,Kana Wu,Andrew T. Chan,Reiko Nishihara,Charles S. Fuchs,Charles S. Fuchs,Jeffrey A. Meyerhardt,Marios Giannakis,Marios Giannakis,Marios Giannakis,Shuji Ogino,Jonathan A. Nowak +37 more
TL;DR: Findings suggested that macrophage polarization state, rather than their overall density, was associated with cancer-specific survival, with M1- and M2-like macrophages phenotypes exhibiting distinct prognostic roles.
Journal ArticleDOI
Antibiotic prophylaxis in hematopoietic stem cell transplantation. A meta-analysis of randomized controlled trials.
Shun Ichi Kimura,Yu Akahoshi,Hirofumi Nakano,Tomotaka Ugai,Hidenori Wada,Ryoko Yamasaki,Yuko Ishihara,Koji Kawamura,Kana Sakamoto,Masahiro Ashizawa,Miki Sato,Kiriko Terasako-Saito,Hideki Nakasone,Misato Kikuchi,Rie Yamazaki,Shinichi Kako,Junya Kanda,Aki Tanihara,Junji Nishida,Yoshinobu Kanda +19 more
TL;DR: Systemic antibiotic prophylaxis successfully reduced the incidence of infection and there was no significant impact on mortality in hematopoietic stem cell transplantation recipients, according to a meta-analysis.
Journal ArticleDOI
Risk factors for pre- and post-engraftment bloodstream infections after allogeneic hematopoietic stem cell transplantation.
Misato Kikuchi,Yu Akahoshi,Hirofumi Nakano,Tomotaka Ugai,Hidenori Wada,Ryoko Yamasaki,Kana Sakamoto,Koji Kawamura,Yuko Ishihara,Miki Sato,Masahiro Ashizawa,Kiriko Terasako-Saito,Shun-ichi Kimura,Rie Yamazaki,Junya Kanda,Shinichi Kako,Junji Nishida,Yoshinobu Kanda +17 more
TL;DR: Bloodstream infections are frequently observed after allogeneic hematopoietic stem cell transplant (HSCT), and could cause morbidity and mortality.
Journal ArticleDOI
Is early-onset cancer an emerging global epidemic? Current evidence and future implications
Tomotaka Ugai,Naoko Sasamoto,Hwa-Young Lee,Mariko Ando,Mingyang Song,Rulla M. Tamimi,Ichiro Kawachi,Peter T. Campbell,Edward Giovannucci,Elisabete Weiderpass,Timothy R. Rebbeck,Shuji Ogino +11 more
TL;DR: The authors describe the emerging global increase in the incidence of early-onset cancers globally and suggest measures that are likely to reduce the burden of cancers and other chronic non-communicable diseases.