T
Torsten Groesser
Researcher at Lawrence Berkeley National Laboratory
Publications - 16
Citations - 375
Torsten Groesser is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: DNA repair & Relative biological effectiveness. The author has an hindex of 9, co-authored 16 publications receiving 333 citations. Previous affiliations of Torsten Groesser include Technical University of Denmark.
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Journal ArticleDOI
Promotion of Homologous Recombination and Genomic Stability by RAD51AP1 via RAD51 Recombinase Enhancement
Claudia Wiese,Eloise Dray,Torsten Groesser,Joseph San Filippo,Idina Shi,David W. Collins,Miaw Sheue Tsai,Gareth J. Williams,Björn Rydberg,Patrick Sung,David Schild +10 more
TL;DR: In this article, it was shown that the RAD51 associated protein 1 (RAD51AP1) is a RAD51-interacting protein whose function has remained elusive, and that it helps maintain genomic integrity via RAD51 recombinase enhancement.
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Lack of Bystander Effects from High-LET Radiation for Early Cytogenetic End Points
TL;DR: The data suggest that DNA damage and cytogenetic changes are not induced in bystander cells, and it is possible that the epigenetic status of the specific cell line or the precise culture conditions and medium supplements, such as serum, may be critical for inducing bystander effects.
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NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability
Ann C. Parplys,Weixing Zhao,Neelam Sharma,Torsten Groesser,Fengshan Liang,David G. Maranon,Stanley G. Leung,Kirsten Grundt,Eloise Dray,Rupa Idate,Anne Carine Østvold,David Schild,Patrick Sung,Claudia Wiese +13 more
TL;DR: The results show that NUCKS1 is a chromatin-associated protein with a role in the DNA damage response and in HR, a DNA repair pathway critical for tumor suppression, and its functional loss leads to a slow down in DNA replication fork progression.
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Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability.
Kelly S. Trego,Torsten Groesser,Albert R. Davalos,Ann C. Parplys,Weixing Zhao,Michael R. Nelson,Ayesu Hlaing,Brian Shih,Björn Rydberg,Janice M. Pluth,Miaw Sheue Tsai,Jan H.J. Hoeijmakers,Patrick Sung,Claudia Wiese,Judith Campisi,Judith Campisi,Priscilla K. Cooper +16 more
TL;DR: These unexpected findings establish XPG as an HRR protein with important roles in genome stability and suggest how XPG defects produce severe clinical consequences including cancer and accelerated aging.
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Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions.
Torsten Groesser,Hang Chang,Gerald V. Fontenay,James Chen,Sylvain V. Costes,Mary Helen Barcellos-Hoff,Bahram Parvin,Björn Rydberg +7 more
TL;DR: The disappearance of radiation-induced γ-H2AX and 53BP1 foci in HMEC has different dynamics that depend on radiation quality and proliferation status, and the general patterns do not depend on the cell culture condition.