C
Claudia Wiese
Researcher at Colorado State University
Publications - 43
Citations - 1849
Claudia Wiese is an academic researcher from Colorado State University. The author has contributed to research in topics: RAD51 & Homologous recombination. The author has an hindex of 21, co-authored 38 publications receiving 1499 citations. Previous affiliations of Claudia Wiese include Lawrence Berkeley National Laboratory.
Papers
More filters
Journal ArticleDOI
BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing
Weixing Zhao,Justin B. Steinfeld,Fengshan Liang,Xiaoyong Chen,David G. Maranon,Chu Jian Ma,Youngho Kwon,Timsi Rao,Weibin Wang,Chen Sheng,Xuemei Song,Yanhong Deng,Judit Jimenez-Sainz,Lucy Lu,Ryan B. Jensen,Yong Xiong,Gary M. Kupfer,Claudia Wiese,Eric C. Greene,Patrick Sung +19 more
TL;DR: The results identify a late role of BRCA1–BARD1 in homologous recombination, an attribute of the tumour suppressor complex that could be targeted in cancer therapy.
Journal ArticleDOI
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
Eloise Dray,Julia Etchin,Claudia Wiese,Dorina Saro,Gareth J. Williams,Michal Hammel,Xiong Yu,Vitold E. Galkin,Dongqing Liu,Miaw-Sheue Tsai,Shirley M.-H. Sy,Shirley M.-H. Sy,David Schild,Edward H. Egelman,Junjie Chen,Patrick Sung +15 more
TL;DR: This work documents a new function of PALB2: to enhance RAD51's ability to form the D loop, and demonstrates the multifaceted role of PALb2 in chromosome damage repair.
Journal ArticleDOI
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry
Weixing Zhao,Sivaraja Vaithiyalingam,Joseph San Filippo,David G. Maranon,Judit Jimenez-Sainz,Gerald V. Fontenay,Youngho Kwon,Stanley G. Leung,Lucy Lu,Ryan B. Jensen,Walter J. Chazin,Claudia Wiese,Claudia Wiese,Patrick Sung +13 more
TL;DR: By targeting RPA and mimicking DNA, DSS1 functions with BRCA2 in a two-component homologous recombination mediator complex in genome maintenance and tumor suppression and may provide a paradigm for understanding the roles of D SS1 in other biological processes.
Journal ArticleDOI
Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells.
Claudia Wiese,David W. Collins,Joanna S. Albala,Larry H. Thompson,Amy Kronenberg,David Schild +5 more
TL;DR: It is argued that there are at least two complexes of Rad51 paralogs in human cells, both containing Rad51C, and Rad51 is not found in these complexes.
Journal ArticleDOI
Promotion of Homologous Recombination and Genomic Stability by RAD51AP1 via RAD51 Recombinase Enhancement
Claudia Wiese,Eloise Dray,Torsten Groesser,Joseph San Filippo,Idina Shi,David W. Collins,Miaw Sheue Tsai,Gareth J. Williams,Björn Rydberg,Patrick Sung,David Schild +10 more
TL;DR: In this article, it was shown that the RAD51 associated protein 1 (RAD51AP1) is a RAD51-interacting protein whose function has remained elusive, and that it helps maintain genomic integrity via RAD51 recombinase enhancement.