T
Tran Thi Nhu Thuy
Researcher at Boston Children's Hospital
Publications - 14
Citations - 1286
Tran Thi Nhu Thuy is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Dengue fever & Medicine. The author has an hindex of 8, co-authored 9 publications receiving 1190 citations.
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Journal ArticleDOI
Poliomyelitis-like illness due to Japanese encephalitis virus.
Tom Solomon,Rachel Kneen,Nguyen Minh Dung,Vo Cong Khanh,Tran Thi Nhu Thuy,Do Quang Ha,Nicholas P. J. Day,Ananda Nisalak,David W. Vaughn,Nicholas J. White +9 more
TL;DR: Compared with Jev-negative patients, weakness in JEV-infected children was more rapid in onset, tended to be asymmetrical, but was less likely to involve the arms, and nerve conduction and electromyographic studies indicated damage to the anterior horn cells.
Journal ArticleDOI
Multicentre prospective study on dengue classification in four South-east Asian and three Latin American countries
Neal Alexander,Angel Balmaseda,Ivo C. B. Coelho,E Dimaano,Tran Tinh Hien,Nguyen Thanh Hung,Thomas Jänisch,Axel Kroeger,Lucy Chai See Lum,Eric Martinez,João Bosco Siqueira,Tran Thi Nhu Thuy,Iris Villalobos,Elci Villegas,Bridget Wills +14 more
TL;DR: Evaluation of the existing WHO dengue classification across all age groups and a wide geographical range and a revised evidence‐based classification that would better reflect clinical severity are evaluated.
Journal ArticleDOI
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
Chiea Chuen Khor,Chiea Chuen Khor,Tran Nguyen Bich Chau,Junxiong Pang,Junxiong Pang,Sonia Davila,Sonia Davila,Hoang Truong Long,Hoang Truong Long,Rick Twee-Hee Ong,Sarah J. Dunstan,Bridget Wills,Jeremy Farrar,Ta Van Tram,Tran Thi Gan,Nguyen Thi Nguyet Binh,Le Trung Tri,Le Bich Lien,Nguyen Minh Tuan,Nguyen Thi Hong Tham,Mai Ngoc Lanh,Nguyen Minh Nguyet,Nguyen Trong Hieu,Nguyen Van Vinh Chau,Tran Thi Nhu Thuy,Dennis E.K. Tan,Anavaj Sakuntabhai,Anavaj Sakuntabhai,Yik Ying Teo,Yik Ying Teo,Martin L. Hibberd,Martin L. Hibberd,Cameron P. Simmons +32 more
TL;DR: A genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam and an independent Vietnamese sample carried out, identifying two loci associated with susceptibility to DSS in people with dengue, suggesting possible mechanisms for this severe complication of d Dengue.
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Maternal antibody and viral factors in the pathogenesis of dengue virus in infants.
Cameron P. Simmons,Tran Nguyen Bich Chau,Tran Thi Nhu Thuy,Nguyen Minh Tuan,Dang Minh Hoang,Nguyen Thanh Thien,Le Bich Lien,Nguyen Thien Quy,Nguyen Trong Hieu,Tran Tinh Hien,Catriona McElnea,Paul R. Young,Steve S. Whitehead,Nguyen Thanh Hung,Jeremy Farrar +14 more
TL;DR: It is suggested that viral burden may not solely explain severe dengue in infants and that neutralizing antibody is a reasonable but not absolute marker of protective immunity in infants.
Journal ArticleDOI
Dengue in Vietnamese Infants—Results of Infection-Enhancement Assays Correlate with Age-Related Disease Epidemiology, and Cellular Immune Responses Correlate with Disease Severity
Tran Nguyen Bich Chau,Nguyen Than Ha Quyen,Tran Thi Nhu Thuy,Nguyen Minh Tuan,Dang Minh Hoang,Nguyen Thi Phuong Dung,Le Bich Lien,Nguyen Thien Quy,Nguyen Trong Hieu,Lu Thi Minh Hieu,Tran Tinh Hien,Nguyen Thanh Hung,Jeremy Farrar,Cameron P. Simmons +13 more
TL;DR: A model of dengue pathogenesis in infants whereby antibody-dependent enhancement of infection explains the age-related case epidemiology and could account for antigen-driven immune activation and its association with disease severity is supported.