Ursula Fünfschilling

TL;DR: By in vivo magnetic resonance spectroscopy, brain lactate concentrations in mutants were increased compared with controls, but were detectable only in mice exposed to volatile anaesthetics, which indicates that aerobic glycolysis products derived from oligodendrocytes are rapidly metabolized within white matter tracts.

TL;DR: It is concluded that at least some adult neurons no longer require endogenous cholesterol synthesis and can fully meet their cholesterol needs by uptake from their surrounding.

TL;DR: It is found that cortical projection neurons synthesize cholesterol during their entire lifetime and at all stages, they can also benefit from glial support, which may have implications for the understanding of neurodegenerative diseases.

TL;DR: It is proposed that M6 proteins are required for proper extension and guidance of callosal axons that follow one of the most complex trajectories in the mammalian nervous system.

TL;DR: The NeuroDloxP mouse mutant will be a valuable tool to study the developmental and adult function of NeuroD in nervous system and pancreas.