U
Urszula Krajewska
Researcher at Medical University of Łódź
Publications - 69
Citations - 1628
Urszula Krajewska is an academic researcher from Medical University of Łódź. The author has contributed to research in topics: Ligand & Pyrazole. The author has an hindex of 21, co-authored 69 publications receiving 1437 citations.
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Comparison of PrestoBlue and MTT assays of cellular viability in the assessment of anti-proliferative effects of plant extracts on human endothelial cells
TL;DR: Two in vitro cytotoxicity assays, new (PB) and classic (MTT) are compared in the assessment of viability of human umbilical vein endothelial cells (HUVECs) in the presence of selected plant extracts and fluorometric PrestoBlue assay is recommended.
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Cytotoxic effects, alkylating properties and molecular modelling of coumarin derivatives and their phosphonic analogues.
TL;DR: Using regression analysis QSAR, a relationship between biological activity and the physicochemical properties of the test compounds is found and their cytotoxic effect increases with an increase of the hydrophobic parameters in the region of the substituents at the 2-, 3- and 4-positions of the benzopyrone skeleton of 4-6.
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Novel Synthesis, Cytotoxic Evaluation, and Structure−Activity Relationship Studies of a Series of α-Alkylidene-γ-lactones and Lactams
Tomasz Janecki,Edyta Blaszczyk,Kazimierz Studzian,Anna Janecka,Urszula Krajewska,Marek Rozalski +5 more
TL;DR: In this paper, 3.5-Alkyl and 5-arylalkyl-3-methylenedihydrofuran-2-ones were synthesized utilizing ethyl 2-diethoxyphosphoryl-4-nitroalkanoates 9a−e as common intermediates.
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Chemical Composition and Biological Activities of Essential Oil from Salvia sclarea Plants Regenerated in vitro
Łukasz Kuźma,Danuta Kalemba,Marek Rozalski,Barbara Różalska,Marzena Więckowska-Szakiel,Urszula Krajewska,Halina Wysokińska +6 more
TL;DR: The essential oils obtained by hydrodistillation of dried aerial parts of Salvia sclarea L. plants, regenerated in vitro and reproduced from seeds, were analyzed by GC and GC-MS and showed antimicrobial and cytotoxic activity.
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Biological evaluation of novel Pt(II) and Pd(II) complexes with pyrazole-containing ligands
Elzbieta Budzisz,Urszula Krajewska,Marek Rozalski,Agata Szulawska,Malgorzata Czyz,Barbara Nawrot +5 more
TL;DR: The cis-[Pt(1b)2Cl2] complex (3b) was the most potent alkylating agent in a Preussmann test, in comparison with the other test compounds and cis-platin, and both complexes were remarkably less toxic to human umbilical vein endothelial cells (HUVECs).