V
Valentina d'Escamard
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 25
Citations - 1396
Valentina d'Escamard is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Fibromuscular dysplasia & Genome-wide association study. The author has an hindex of 10, co-authored 22 publications receiving 1021 citations.
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Journal ArticleDOI
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Solene M. Evrard,Laura Lecce,Katherine C. Michelis,Aya Nomura-Kitabayashi,Gaurav Pandey,K-Raman Purushothaman,Valentina d'Escamard,Jennifer Li,Lahouaria Hadri,Kenji Fujitani,Pedro R. Moreno,Ludovic Benard,Pauline Rimmele,Ariella Cohain,Brigham H. Mecham,Gwendalyn J. Randolph,Elizabeth G. Nabel,Roger J. Hajjar,Valentin Fuster,Valentin Fuster,Manfred Boehm,Jason C. Kovacic +21 more
TL;DR: It is shown that EndMT contributes to atherosclerotic patho-biology and is associated with complex plaques that may be related to clinical events, and the extent of EndMT correlates with an unstable plaque phenotype, which appears driven by altered collagen-MMP production in EndMT-derived cells.
Journal ArticleDOI
Correction: Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Solene M. Evrard,Laura Lecce,Katherine C. Michelis,Aya Nomura-Kitabayashi,Gaurav Pandey,K-Raman Purushothaman,Valentina d'Escamard,Jennifer Li,Lahouaria Hadri,Kenji Fujitani,Pedro Moreno,Ludovic Benard,Pauline Rimmele,Ariella Cohain,Brigham H. Mecham,Gwendalyn J. Randolph,Elizabeth G. Nabel,Roger J. Hajjar,Valentin Fuster,Manfred Boehm,Jason C. Kovacic +20 more
TL;DR: In this Article, the catalogue number for the anti-Fap-Alexa Fluor 647 antibody is listed incorrectly and should have read bs-5758R-A647 instead of b s-5760R- a647.
Journal ArticleDOI
PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance.
Soto Romuald Kiando,Soto Romuald Kiando,Nathan R. Tucker,Nathan R. Tucker,Luis Jaime Castro-Vega,Luis Jaime Castro-Vega,Alexander Katz,Valentina d'Escamard,Cyrielle Treard,Cyrielle Treard,Daniel Fraher,Daniel Fraher,Juliette Albuisson,Juliette Albuisson,Daniella Kadian-Dodov,Zi Ye,Erin Austin,Min-Lee Yang,Kristina L. Hunker,Cristina Barlassina,Daniele Cusi,Pilar Galan,Jean Philippe Empana,Jean Philippe Empana,Xavier Jouven,Xavier Jouven,Anne Paule Gimenez-Roqueplo,Anne Paule Gimenez-Roqueplo,Patrick Bruneval,Patrick Bruneval,Esther Soo Hyun Kim,Jeffrey W. Olin,Heather L. Gornik,Michel Azizi,Pierre-François Plouin,Pierre-François Plouin,Patrick T. Ellinor,Patrick T. Ellinor,Iftikhar J. Kullo,David J. Milan,David J. Milan,Santhi K. Ganesh,Pierre Boutouyrie,Pierre Boutouyrie,Jason C. Kovacic,Xavier Jeunemaitre,Xavier Jeunemaitre,Nabila Bouatia-Naji,Nabila Bouatia-Naji +48 more
TL;DR: The first susceptibility locus for FMD is reported and evidence for a complex genetic pattern of inheritance and indices of shared pathophysiology between FMD and other cardiovascular and neurovascular diseases is provided.
Journal ArticleDOI
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
David Adlam,Timothy M. Olson,Nicolas Combaret,Jason C. Kovacic,Siiri E. Iismaa,Abtehale Al-Hussaini,Megan M. O’Byrne,Sara Bouajila,Adrien Georges,K Mishra,Peter S. Braund,Valentina d'Escamard,S Huang,M Margaritis,Christopher P. Nelson,M. De Andrade,Daniella Kadian-Dodov,C A Welch,S Mazurkiewicz,Xavier Jeunemaitre,Wong Cmy.,Eleni Giannoulatou,Michael J. Sweeting,David W.M. Muller,Alice Wood,Lucy McGrath-Cadell,Diane Fatkin,Sally L. Dunwoodie,Richard P. Harvey,Cameron J. Holloway,Empana J-P.,Xavier Jouven,Jeffrey W. Olin,Rajiv Gulati,Marysia S. Tweet,Sharonne N. Hayes,Nilesh J. Samani,Robert M. Graham,Pascal Motreff,Nabila Bouatia-Naji,Nabila Bouatia-Naji +40 more
TL;DR: The first genetic risk factor for SCAD was identified in the largest study conducted to date for this condition, and this genetic link may contribute to the clinical overlap between SCAD and FMD.
Journal ArticleDOI
Coronary Artery Manifestations of Fibromuscular Dysplasia
Katherine C. Michelis,Jeffrey W. Olin,Jeffrey W. Olin,Daniella Kadian-Dodov,Valentina d'Escamard,Jason C. Kovacic,Jason C. Kovacic +6 more
TL;DR: The clinical course of FMD involving the coronary arteries is reviewed, guidance for diagnosis and treatment strategies are provided and a conservative approach is generally preferred.