V
Vincent T.H.B.M. Smit
Researcher at Leiden University Medical Center
Publications - 163
Citations - 11210
Vincent T.H.B.M. Smit is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Breast cancer & Endometrial cancer. The author has an hindex of 50, co-authored 147 publications receiving 8598 citations. Previous affiliations of Vincent T.H.B.M. Smit include Loyola University Medical Center & The Breast Cancer Research Foundation.
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Journal ArticleDOI
Pediatric germ cell tumors presenting beyond childhood
J. W. Oosterhuis,J. Stoop,Martin A. Rijlaarsdam,Katharina Biermann,Vincent T.H.B.M. Smit,Remko Hersmus,Leendert H. J. Looijenga +6 more
TL;DR: The present report broadens the concept of earlier reported benign teratomas of the post‐pubertal testis to the full spectrum of pediatric TGCT, and lends credence to the concept that TGCT should according to their pathogenesis be classified into the previously proposed types.
Journal ArticleDOI
The prognostic value of apoptotic and proliferative markers in breast cancer
C.C. Engels,Francesca Ruberta,Esther M. de Kruijf,Gabi W. van Pelt,Vincent T.H.B.M. Smit,Gerrit-Jan Liefers,Tomoko Matsushima,Masaki Shibayama,Hideki Ishihara,Cornelis J.H. van de Velde,Peter J. K. Kuppen +10 more
TL;DR: The apoptotic–proliferative subtypes that are presented in this study represent a clinical prognostic profile with solid underlying biological rationale and pose a promising method for accurate identification of grade I BC patients in need of an aggressive therapeutic approach, thus contributing to precision medicine in BC disease.
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Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer.
Elke E M Peters,Carla Bartosch,W. Glenn McCluggage,Catherine Genestie,Sigurd F. Lax,Remi A. Nout,Jan Oosting,Naveena Singh,Huub C S H Smit,Vincent T.H.B.M. Smit,Koen Van de Vijver,Tjalling Bosse +11 more
TL;DR: A study is designed to evaluate interobserver agreement in discriminating true LVSI from LVSI mimics and reproducibility of grading extent of LVSI in EC.
Journal ArticleDOI
Prognostic significance of periodic acid-Schiff-positive patterns in primary breast cancer and its lymph node metastases.
Jeroen T. Buijs,Anne-Marie Cleton,Vincent T.H.B.M. Smit,Clemens W.G.M. Löwik,Socrates E. Papapoulos,Gabri van der Pluijm +5 more
TL;DR: The presence of PAS+ networks in lymph node metastases is a new, reliable and convenient indicator for prognosis of breast cancer patients.
Journal ArticleDOI
Searching for metastases in ovarian tissue before autotransplantation: a tailor-made approach
Ellen J. Hoekman,Vincent T.H.B.M. Smit,Timothy P. Fleming,L. A. Louwe,Gert Jan Fleuren,Carina G. J. M. Hilders +5 more
TL;DR: The tailor-made approach consisted of patient-specific tumor markers which were used to search for ovarian micrometastases and found evidence of metastatic disease within the fallopian tube of a patient with intraperitoneal metastatic esophageal adenocarcinoma.