V
Vincenzo Rossi
Researcher at University of Milan
Publications - 53
Citations - 2624
Vincenzo Rossi is an academic researcher from University of Milan. The author has contributed to research in topics: Minimal residual disease & Leukemia. The author has an hindex of 27, co-authored 53 publications receiving 2567 citations. Previous affiliations of Vincenzo Rossi include University of Milano-Bicocca & Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.
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Journal ArticleDOI
Early Detection of Relapse by Prospective Reverse Transcriptase-Polymerase Chain Reaction Analysis of the PML/RARα Fusion Gene in Patients With Acute Promyelocytic Leukemia Enrolled in the GIMEMA-AIEOP Multicenter “AIDA” Trial
Daniela Diverio,Vincenzo Rossi,Giuseppe Avvisati,S. De Santis,A. Pistilli,Fabrizio Pane,G. Saglio,Giovanni Martinelli,Maria Concetta Petti,Alessandra Santoro,P. G. Pelicci,Franco Mandelli,Andrea Biondi,F. Lo Coco +13 more
TL;DR: Salvage treatment in patients enrolled in the GIMEMA trial AIDA is now anticipated at the time of molecular relapse, defined as the conversion to PCR positivity in two successive BM samplings during follow-up.
Journal ArticleDOI
Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia
F Lo Coco,Daniela Diverio,Giuseppe Avvisati,William Arcese,Maria Concetta Petti,Giovanna Meloni,Franco Mandelli,P P Pandolfi,Fausto Grignani,Pier Giuseppe Pelicci,Andrea Biondi,Vincenzo Rossi,Giuseppe Masera,T Barbui,Alessandro Rambaldi +14 more
TL;DR: Tests for a unique fusion transcript, PML/RAR alpha, in 35 APL patients who were in apparent remission after various treatments found 11 of 13 patients who tested positive 4 months after achieving remission were in relapse 1-4 months later.
Journal ArticleDOI
Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype.
Giovanni Cazzaniga,Maria Grazia Dell’Oro,Cristina Mecucci,Emanuela Giarin,Riccardo Masetti,Vincenzo Rossi,Franco Locatelli,Massimo F. Martelli,Giuseppe Basso,Andrea Pession,Andrea Biondi,Brunangelo Falini +11 more
TL;DR: The NPM1 mutation is a frequent abnormality in AML patients without known genetic marker; the mutation may represent a new target to monitor minimal residual disease inAML and a potential candidate for alternative and targeted treatments.
Journal ArticleDOI
Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction
Andrea Biondi,Alessandro Rambaldi,PP Pandolfi,Vincenzo Rossi,Giovanni Giudici,Myriam Alcalay,F. Lo Coco,D Diverio,Enrico Pogliani,EM Lanzi +9 more
TL;DR: It is concluded that PCR amplification of the myl/RAR-alpha junctions represents the easiest and rapid method for diagnosis and monitoring of the APL clone.
Journal ArticleDOI
Extracorporeal photochemotherapy is accompanied by increasing levels of circulating CD4+CD25+GITR+Foxp3+CD62L+ functional regulatory T-cells in patients with graft-versus-host disease.
Ettore Biagi,Iolanda Di Biaso,Veronica Leoni,Giuseppe Gaipa,Vincenzo Rossi,Cristina Bugarin,Giuliano Renoldi,Matteo Parma,Adriana Balduzzi,Paolo Perseghin,Andrea Biondi +10 more
TL;DR: This study shows a time correlation between ECP and increasing percentages of circulating functional T-regs, and shows that cell-to-cell contact was necessary to exert inhibitory activity, which needs to be confirmed on larger series to determine the actual role of T- Reg in mediating the clinical effect of ECP.