V
Virginia B. Kraus
Researcher at Duke University
Publications - 495
Citations - 24767
Virginia B. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Osteoarthritis & Synovial fluid. The author has an hindex of 75, co-authored 452 publications receiving 19648 citations. Previous affiliations of Virginia B. Kraus include Howard Hughes Medical Institute & Research Triangle Park.
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Journal ArticleDOI
OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
Raveendhara R. Bannuru,Mikala C. Osani,Elizaveta E. Vaysbrot,Nigel K Arden,Nigel K Arden,Kim L Bennell,Sita M A Bierma-Zeinstra,Virginia B. Kraus,L.S. Lohmander,J.H. Abbott,Mohit Bhandari,Francisco J. Blanco,R. Espinosa,Ida K. Haugen,J. Lin,Lisa A. Mandl,Eeva Moilanen,Norimasa Nakamura,Lynn Snyder-Mackler,Thomas H. Trojian,Malcolm J. Underwood,Malcolm J. Underwood,Timothy E. McAlindon +22 more
TL;DR: These guidelines offer comprehensive and patient-centered treatment profiles for individuals with Knee, Hip, and Polyarticular OA that are derived from expert consensus and based on objective review of high-quality meta-analytic data.
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Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Srikumar Chellappan,Virginia B. Kraus,B Kroger,K Munger,Peter M. Howley,W C Phelps,Joseph R. Nevins +6 more
TL;DR: The ability of E1A, the simian virus 40 large tumor antigen, and E7 to dissociate the E2F-pRb complex may be a common activity of these viral proteins that has evolved to stimulate quiescent cells into a proliferating state so that viral replication can proceed efficiently.
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Colchicine—Update on mechanisms of action and therapeutic uses
TL;DR: The therapeutic use of colchicine has extended beyond gouty arthritis and familial Mediterranean fever, to osteoarthritis, pericarditis, and atherosclerosis, and further understanding of the mechanisms of action underlying the therapeutic efficacy will lead to its potential use in a variety of conditions.
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Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use.
TL;DR: The goals of this review are to stimulate use of standardized nomenclature for OA that could serve as building blocks for describing OA and defining OA phenotypes to provide unifying disease concepts for a heterogeneous disorder.
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Basic methods in histopathology of joint tissues.
TL;DR: This chapter describes five basic staining procedures appropriate for macroscopic and histologic visualization and scoring of cartilage proteoglycan and collagen content (toluidine blue/safranin O and picrosirius red/Goldner's trichrome).