Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use.
TLDR
The goals of this review are to stimulate use of standardized nomenclature for OA that could serve as building blocks for describing OA and defining OA phenotypes to provide unifying disease concepts for a heterogeneous disorder.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2015-08-01 and is currently open access. It has received 412 citations till now.read more
Citations
More filters
Journal ArticleDOI
Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.
TL;DR: In this paper, a review of hip and knee OA is presented, focusing on the most common reason for activity limitation in adults. But, the authors do not discuss the treatment of OA in the context of total joint replacement.
Journal ArticleDOI
Animal models of osteoarthritis: classification, update, and measurement of outcomes.
TL;DR: This review summarizes the current understanding of the disease pathogenesis, invasive and non-invasive animal models, imaging modalities, and pain assessment techniques in the animals.
Journal ArticleDOI
Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future
Morten A. Karsdal,M. Michaelis,Christoph Ladel,Anne Sofie Siebuhr,Asger Reinstrup Bihlet,Jeppe Ragnar Andersen,Hans Guehring,C. Christiansen,Anne-Christine Bay-Jensen,Virginia B. Kraus +9 more
TL;DR: This review of several ambitious but failed attempts to develop joint structure-modifying treatments for OA suggests that these failures arose from unrealistic hypotheses, sub-optimal selection of patient populations or drug dose, and/or inadequate sensitivity of the trial endpoints.
Journal ArticleDOI
Update on the epidemiology, risk factors and disease outcomes of osteoarthritis
TL;DR: The occurrence and risk factors for OA are reviewed and patient-reported outcome measures that have been used for the assessment of the disease are considered.
Journal ArticleDOI
The Role of Inflammation in the Pathogenesis of Osteoarthritis.
Yoke Yue Chow,Kok-Yong Chin +1 more
TL;DR: This review is aimed at summarizing the previous studies highlighting the involvement of inflammation in the pathogenesis of osteoarthritis, a common chronic debilitating joint disease mainly affecting the elderly.
References
More filters
Journal ArticleDOI
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more
TL;DR: Variables from the medical history, physical examination, laboratory tests, and radiographs were used to develop sets of criteria that serve different investigative purposes and these proposed criteria utilize classification trees, or algorithms.
Journal ArticleDOI
Heart Disease and Stroke Statistics—2014 Update A Report From the American Heart Association
Alan S. Go,Dariush Mozaffarian,Véronique L. Roger,Emelia J. Benjamin,Jarett D. Berry,Michael J. Blaha,Shifan Dai,Earl S. Ford,Caroline S. Fox,Sheila Franco,Heather J. Fullerton,Cathleen Gillespie,Susan M. Hailpern,John A. Heit,Virginia J. Howard,Mark D. Huffman,Suzanne E. Judd,Brett M. Kissela,Steven J. Kittner,Daniel T. Lackland,Judith H. Lichtman,Lynda D. Lisabeth,Rachel H. Mackey,David J. Magid,Gregory M. Marcus,Ariane Marelli,David B. Matchar,Darren K. McGuire,Emile R. Mohler,Claudia S. Moy,Michael E. Mussolino,Robert W. Neumar,Graham Nichol,Dilip K. Pandey,Nina P. Paynter,Matthew J. Reeves,Paul D. Sorlie,Joel Stein,Amytis Towfighi,Tanya N. Turan,Salim S. Virani,Nathan D. Wong,Daniel Woo,Melanie B. Turner +43 more
TL;DR: Author(s): Go, Alan S; Mozaffarian, Dariush; Roger, Veronique L; Benjamin, Emelia J; Berry, Jarett D; Blaha, Michael J; Dai, Shifan; Ford, Earl S; Fox, Caroline S; Franco, Sheila; Fullerton, Heather J; Gillespie, Cathleen; Hailpern, Susan M; Heit, John A; Howard, Virginia J; Huffman, Mark D; Judd
Journal ArticleDOI
The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection
Martin Rudwaleit,D. van der Heijde,Robert Landewé,Joachim Listing,Nurullah Akkoc,J Brandt,Jürgen Braun,C.T. Chou,Eduardo Collantes-Estevez,Maxime Dougados,Feng Huang,Jieruo Gu,Muhammad Asim Khan,Yesim Kirazli,Walter P. Maksymowych,Herman Mielants,Inge Juul Sørensen,Salih Ozgocmen,Euthalia Roussou,R. Valle-Oñate,Ulrich Weber,James Cheng-Chung Wei,Joachim Sieper +22 more
TL;DR: The new ASAS classification criteria for axial SpA can reliably classify patients for clinical studies and may help rheumatologists in clinical practice in diagnosing axial spondyloarthritis in those with chronic back pain.
Journal ArticleDOI
Osteoarthritis cartilage histopathology: grading and staging
Kenneth P.H. Pritzker,Kenneth P.H. Pritzker,Sergio A. Jimenez,Keld Ostergaard,J.-P. Pelletier,P A Revell,Donald Salter,W.B. van den Berg +7 more
TL;DR: The OARSI cartilage OA histopathology grading system appears consistent and simple to apply as discussed by the authors, however, further studies are required to confirm the system's utility, as well as their reproducibility and validity.
Journal ArticleDOI
A systematic review of hip fracture incidence and probability of fracture worldwide
TL;DR: Worldwide, there are marked variations in hip fracture rates and in the 10-year probability of major osteoporotic fractures that cannot be explained by the often multiple sources of error in the ascertainment of cases or the catchment population.
Related Papers (5)
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more