V
Virginie Gandemer
Researcher at University of Rennes
Publications - 136
Citations - 3388
Virginie Gandemer is an academic researcher from University of Rennes. The author has contributed to research in topics: Medicine & Transplantation. The author has an hindex of 30, co-authored 103 publications receiving 2755 citations. Previous affiliations of Virginie Gandemer include European Organisation for Research and Treatment of Cancer.
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Journal ArticleDOI
Autosomal dominant STAT3 deficiency and hyper-IgE syndrome: molecular, cellular, and clinical features from a French national survey.
Marie-Olivia Chandesris,Isabelle Melki,Angels Natividad,Anne Puel,Claire Fieschi,Ling Yun,Caroline Thumerelle,Eric Oksenhendler,David Boutboul,Caroline Thomas,Cyrille Hoarau,Yvon Lebranchu,Jean-Louis Stephan,Celine Cazorla,Nathalie Aladjidi,Marguerite Micheau,Fran cois Tron,André Baruchel,Vincent Barlogis,Gilles Palenzuela,Catherine Mathey,Stephane Dominique,Gerard Body,Martine Munzer,Fanny Fouyssac,Rolland Jaussaud,Brigitte Bader-Meunier,Nizar Mahlaoui,Stéphane Blanche,Marianne Debré,Muriel Le Bourgeois,Virginie Gandemer,Nathalie Lambert,Virginie Grandin,Stephanie Ndaga,Corinne Jacques,Chantal Harre,Monique Forveille,Marie-Alexandra Alyanakian,Anne Durandy,Christine Bodemer,Felipe Suarez,Olivier Hermine,Olivier Lortholary,Jean-Laurent Casanova,Alain Fischer,Capucine Picard +46 more
TL;DR: The prognosis of STAT3 deficiency may be considered good, provided that multiple prophylactic measures, including IgG infusions, are implemented, as demonstrated by the large decrease in pneumonia recurrence.
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Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study
Andrea Biondi,Martin Schrappe,Paola De Lorenzo,Anders Castor,Giovanna Lucchini,Virginie Gandemer,Rob Pieters,Jan Stary,Gabriele Escherich,Myriam Campbell,Chi Kong Li,Ajay Vora,Maurizio Aricò,Silja Röttgers,Vaskar Saha,Maria Grazia Valsecchi +15 more
TL;DR: The results suggests that imatinib in conjunction with intensive chemotherapy is well tolerated and might be beneficial for treatment of children with Philadelphia-chromosome-positive ALL.
Journal ArticleDOI
BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy
Sébastien Héritier,Jean-François Emile,Mohamed-Aziz Barkaoui,Caroline Thomas,Sylvie Fraitag,Sabah Boudjemaa,Florence Renaud,Anne Moreau,Michel Peuchmaur,Catherine Chassagne-Clément,Frédérique Dijoud,Valérie Rigau,Despina Moshous,Anne Lambilliotte,Françoise Mazingue,Kamila Kebaili,Jean Miron,Eric Jeziorski,Geneviève Plat,Nathalie Aladjidi,Alina Ferster,Hélène Pacquement,Claire Galambrun,Laurence Brugières,Guy Leverger,Ludovic Mansuy,Catherine Paillard,Anne Deville,Corinne Armari-Alla,Anne Lutun,Marion Gillibert-Yvert,Jean Louis Stephan,Fleur Cohen-Aubart,Julien Haroche,Isabelle Pellier,Frédéric Millot,Brigitte Lescoeur,Virginie Gandemer,Christine Bodemer,Roger Lacave,Zofia Hélias-Rodzewicz,Valérie Taly,Frederic Geissmann,Jean Donadieu +43 more
TL;DR: In children with LCH, BRAF(V600E) mutation was associated with high-risk features, permanent injury, and poor short-term response to chemotherapy, and the impact of BRAF inhibitors for this subgroup of patients who may benefit from targeted therapy.
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New insights into childhood autoimmune hemolytic anemia: a French national observational study of 265 children.
Nathalie Aladjidi,Guy Leverger,Thierry Leblanc,Marie Quitterie Picat,Gérard Michel,Yves Bertrand,Brigitte Bader-Meunier,Alain Robert,Brigitte Nelken,Virginie Gandemer,Hélène Savel,Jean Louis Stephan,Fanny Fouyssac,Julien Jeanpetit,Caroline Thomas,Pierre Rohrlich,André Baruchel,Alain Fischer,Geneviève Chêne,Yves Perel +19 more
TL;DR: This nationwide French cohort is the largest reported study of childhood autoimmune hemolytic anemia and Evans' syndrome is confirmed, and subgroups with genetic predisposition and underlying immune disorders were identified.
Journal ArticleDOI
Classification of and risk factors for hematologic complications in a French national cohort of 102 patients with Shwachman-Diamond syndrome.
Jean Donadieu,Odile Fenneteau,Blandine Beaupain,Sandrine Beaufils,Florence Bellanger,Nizar Mahlaoui,Anne Lambilliotte,Nathalie Aladjidi,Yves Bertrand,Valérie Mialou,Christine Perot,Gérard Michel,Fanny Fouyssac,Catherine Paillard,Virginie Gandemer,Patrick Boutard,Jacques Schmitz,Alain Morali,Thierry Leblanc,Christine Bellanné-Chantelot +19 more
TL;DR: Patients with Shwachman-Diamond syndrome with very early symptoms or cytopenia at diagnosis should be considered at a high risk of severe hematologic complications, malignant or non-malignant.