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Wei Chen

Researcher at University of Sheffield

Publications -  14
Citations -  817

Wei Chen is an academic researcher from University of Sheffield. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 6, co-authored 8 publications receiving 765 citations. Previous affiliations of Wei Chen include Chinese Academy of Sciences.

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Journal ArticleDOI

Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells.

TL;DR: In this paper, the identification and isolation of a population of SOX2+OCT4+ human auditory stem cells from 9-week-old to 11-weekold fetal cochleae (hFASCs) was described.
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Monitoring of gene expression profiles and isolation of candidate genes involved in pollination and fertilization in rice ( Oryza sativa L.) with a 10K cDNA microarray.

TL;DR: The results indicated that this cDNA microarray constructed here is reliable and can be used for monitoring gene expression profiles in rice and the genes that differentially expressed during pollination represent candidate genes for dissecting molecular mechanism of this important biological process in rice.
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Human-derived neural progenitors functionally replace astrocytes in adult mice

TL;DR: It is demonstrated that after transplantation into the cervical spinal cords of adult mice with severe combined immunodeficiency (SCID), human pluripotent stem cell-derived (PSC-derived) neural progenitors migrate a long distance and differentiate to astrocytes that nearly replace their mouse counterparts over a 9-month period.
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The human fetal cochlea can be a source for auditory progenitors/stem cells isolation.

TL;DR: The suitability of the developing fetal cochlea to be used as a source for the extraction of auditory progenitor/stem cells is explored and cultures that express critical markers such as NESTIN, SOX2, GATA3 and PAX2 are established.