Lefu Lan

TL;DR: HopAI1, an effector widely conserved in both plant and animal bacterial pathogens, inhibits the Arabidopsis mitogen-activated protein kinases (MAPKs) activated by exposure to PAMPs, uncovering a mechanism by which Pseudomonas syringae overcomes host innate immunity to promote pathogenesis.

TL;DR: Comparative genome analysis between cultivated rice subspecies shows that there is an overall syntenic relationship between the chromosomes and divergence at the level of single-nucleotide polymorphisms and insertions and deletions, and by contrast, there is little conservation in gene order between rice and Arabidopsis.

TL;DR: It is reported here that phosphorylation occurs to a reactive cysteine residue conserved in the staphylococcal accessary regulator A/MarR family global transcriptional regulator A (MgrA) family of proteins, and is mediated by the eukaryotic-like kinase-phosphatase pair Stk1-Stp1 in Staphylitis aureus.

TL;DR: Results reveal that MexR is a redox regulator that senses peroxide stress to mediate antibiotic resistance in P. aeruginosa.

TL;DR: Virtual screening and optimization of inhibitor structure is used to identify 3,6-disubstituted triazolothiadiazole compounds as inhibitors of sortase, an enzyme that incorporates surface proteins into the staphylococcal envelope that may prevent hospital-acquired S. aureus infection in high-risk patients without the side effects of antibiotics.