Gang Lv

TL;DR: Comparative genome analysis between cultivated rice subspecies shows that there is an overall syntenic relationship between the chromosomes and divergence at the level of single-nucleotide polymorphisms and insertions and deletions, and by contrast, there is little conservation in gene order between rice and Arabidopsis.

TL;DR: A high-quality draft assembly is reported of the 1.74-gigabase genome of A. annua, which is highly heterozygous, rich in repetitive sequences, and contains 63 226 protein-coding genes, one of the largest numbers among the sequenced plant species.

TL;DR: In this paper , the authors comprehensively analyzed genomic, epigenomic and transcriptomic data from 121 osteosarcoma patients and classified them into four subtypes with distinct molecular features and clinical prognosis: (1) immune activated (S-IA), (2) immune suppressed, (3) homologous recombination deficiency dominant, and (4) myC driven.

TL;DR: In this article , a competitive endogenous RNA (ceRNA) regulatory network composed of three circRNAs, three miRNAs and six mRNAs was established for postoperative cognitive dysfunction (POCD).

TL;DR: The findings suggest that targeting mitochondrial bioenergetics might be an effective strategy against cardiac disorders caused by EMD mutations, and a novel nonsense mutation in the EMD gene in a Han Chinese family through high‐throughput sequencing is identified.