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Kevin P. Baker
Researcher at Genentech
Publications - 106
Citations - 4407
Kevin P. Baker is an academic researcher from Genentech. The author has contributed to research in topics: Nucleic acid & Nucleic acid methods. The author has an hindex of 15, co-authored 104 publications receiving 4349 citations.
Papers
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Journal ArticleDOI
Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors
James P. Sheridan,Scot A. Marsters,Robert M. Pitti,Austin L. Gurney,Maya Skubatch,Daryl T. Baldwin,Lakshmi Ramakrishnan,Christa L. Gray,Kevin P. Baker,William I. Wood,Audrey Goddard,Paul J. Godowski,Avi Ashkenazi +12 more
TL;DR: A cell surface mechanism exists for the regulation of cellular responsiveness to pro-apoptotic stimuli in tumor cells.
Patent
Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
Kevin P. Baker,Maureen Beresini,Laura DeForge,Luc Desnoyers,Ellen Filvaroff,Wei-Qiang Gao,Mary E. Gerritsen,Audrey Goddard,Paul J. Godowski,Austin L. Gurney,Steven Sherwood,Victoria Smith,Timothy A. Stewart,Daniel Tumas,Colin K. Watanabe,William I. Wood,Zemin Zhang +16 more
TL;DR: In this paper, the present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polyptides, and vectors and host cells comprising those nucleic amino acid sequences.
Journal ArticleDOI
The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment
Hilary Clark,Austin L. Gurney,Evangeline Abaya,Kevin P. Baker,Daryl T. Baldwin,Jennifer Brush,Jian Chen,Bernard Chow,Clarissa Chui,Craig Crowley,Bridget Currell,Bethanne Deuel,Patrick Dowd,Dan L. Eaton,Jessica Foster,Christopher Grimaldi,Qimin Gu,Philip E. Hass,Sherry Heldens,Arthur J Huang,Hok Seon Kim,Laura Klimowski,Yisheng Jin,Stephanie Johnson,James Lee,Lhney Lewis,Dongzhou Liao,Melanie R. Mark,Edward P. Robbie,Celina Sanchez,Jill Schoenfeld,Somasekar Seshagiri,Laura Simmons,Jennifer Singh,Victoria Smith,Jeremy Stinson,Alicia Vagts,Richard Vandlen,Colin K. Watanabe,David Wieand,Kathryn Woods,Ming-Hong Xie,Daniel G. Yansura,Sothy Yi,Guoying Yu,Jean Yuan,Min Zhang,Zemin Zhang,Audrey Goddard,William I. Wood,Paul J. Godowski +50 more
TL;DR: The SPDI collection should facilitate efforts to better understand intercellular communication, may lead to new understandings of human diseases, and provides potential opportunities for the development of therapeutics.
Patent
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
Kevin P. Baker,Napoleone Ferrara,Hans-Peter Gerber,Mary E. Gerritsen,Audrey Goddard,Paul J. Godowski,Austin L. Gurney,Kenneth J. Hillan,Scot A. Marsters,James Pan,Nicholas F. Paoni,Jean-Philippe Stephan,Colin K. Watanabe,P. Mickey Williams,William I. Wood,Weilan Ye +15 more
TL;DR: In this article, the authors present compositions and methods for stimulating or inhibiting angiogeniesis and/or cardiovascularization in mammals, including humans, using polypeptides or antagonists that have been identified for one or more of these uses.