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Weiping Cai
Researcher at Guangzhou Medical University
Publications - 133
Citations - 3387
Weiping Cai is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Medicine & Randomized controlled trial. The author has an hindex of 23, co-authored 112 publications receiving 2349 citations. Previous affiliations of Weiping Cai include Sun Yat-sen University & University of North Carolina at Chapel Hill.
Papers
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Journal ArticleDOI
Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis.
Leiwen Fu,Bingyi Wang,Tanwei Yuan,Xiaoting Chen,Yunlong Ao,Thomas Fitzpatrick,Peiyang Li,Yiguo Zhou,Yi-Fan Lin,Qibin Duan,Ganfeng Luo,Song Fan,Yong Lu,Anping Feng,Yuewei Zhan,Bowen Liang,Weiping Cai,Lin Zhang,Xiangjun Du,Linghua Li,Yuelong Shu,Huachun Zou +21 more
TL;DR: The majority of COVID-19 cases are symptomatic with a moderate CFR, and patients living in Wuhan, older patients, and those with medical comorbidities tend to have more severe clinical symptoms and higher CFR.
Journal ArticleDOI
Efficacy and Safety of Lopinavir/Ritonavir or Arbidol in Adult Patients with Mild/Moderate COVID-19: An Exploratory Randomized Controlled Trial.
Yueping Li,Zhiwei Xie,Weiyin Lin,Weiping Cai,Chunyan Wen,Yujuan Guan,Xiaoneng Mo,Jian Wang,Yaping Wang,Ping Peng,Xudan Chen,Wenxin Hong,Guangming Xiao,Jinxin Liu,Lieguang Zhang,Fengyu Hu,Feng Li,Fuchun Zhang,Xilong Deng,Linghua Li +19 more
TL;DR: In this paper, an exploratory randomized (2:2:1) controlled trial assessing the efficacy and safety of lopinavir/ritonavir (LPV/r) or arbidol monotherapy for treating patients with mild/moderate COVID-19 was conducted.
Journal ArticleDOI
Expansion of Monocytic Myeloid-Derived Suppressor Cells Dampens T Cell Function in HIV-1-Seropositive Individuals
Aiping Qin,Weiping Cai,Ting Pan,Kang Wu,Qiong Yang,Nina Wang,Yufeng Liu,Dehong Yan,Fengyu Hu,Pengle Guo,Xiaoping Chen,Ling Chen,Hui Zhang,Hui Zhang,Xiaoping Tang,Jie Zhou,Jie Zhou +16 more
TL;DR: Evidence is provided that expansion of monocytic myeloid-derived suppressor cells (M-MDSCs) suppressed T cell function in HIV-1-infected individuals and it is suggested that targeting MDSCs may be a promising strategy for HIV- 1 immunotherapy.
Posted ContentDOI
An exploratory randomized, controlled study on the efficacy and safety of lopinavir/ritonavir or arbidol treating adult patients hospitalized with mild/moderate COVID-19 (ELACOI)
Yueping Li,Zhiwei Xie,Weiyin Lin,Weiping Cai,Chunyan Wen,Yujuan Guan,Xiaoneng Mo,Jian Wang,Yaping Wang,Ping Peng,Xudan Chen,Wenxin Hong,Guangming Xiao,Jinxin Liu,Lieguang Zhang,Fengyu Hu,Feng Li,Fuchun Zhang,Xilong Deng,Linghua Li +19 more
TL;DR: LPV/r or arbidol monotherapy present little benefit for improving the clinical outcome of patients hospitalized with mild/moderate COVID-19 over supportive care.
Journal ArticleDOI
Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection
Liang Shan,Liang Shan,Kai Deng,Kai Deng,Hongbo Gao,Sifei Xing,Adam A. Capoferri,Christine M. Durand,S. Alireza Rabi,Gregory M. Laird,Michelle Kim,Nina N. Hosmane,Hung-Chih Yang,Hao Zhang,Joseph B. Margolick,Linghua Li,Weiping Cai,Ruian Ke,Richard A. Flavell,Richard A. Flavell,Janet D. Siliciano,Robert F. Siliciano,Robert F. Siliciano +22 more
TL;DR: A unique set of properties of CD4+ T cells undergoing effector‐to‐memory transition including temporary upregulation of CCR5 expression and rapid downregulation of cellular gene transcription are described, allowing the establishment of latency.